Company Name: |
Sigma-Aldrich
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Tel: |
021-61415566 800-8193336 |
Email: |
orderCN@merckgroup.com |
Products Intro: |
Product Name:Human Arginase 1 ELISA Purity:for serum, plasma and cell culture supernatants Package:1KT Remarks:RAB1271-1KT
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| Human Arginase 1 ELISA Basic information |
| Human Arginase 1 ELISA Chemical Properties |
| Human Arginase 1 ELISA Usage And Synthesis |
Uses | For research use only. Not for use in diagnostic procedures. Please refer to the attached Protocolfor details. | General Description | The gene encoding arginase 1 (ARG1), spanning 10-15kb on genomic DNA, is localized on human chromosome 6q23.2. It consists of eight exons. The protein consists of 322 amino acids and is expressed in the liver, red blood cells, lactating mammalian glands and the kidney. | Biochem/physiol Actions | Arginase 1 (ARG1) is a liver enzyme involved in the hydrolysis of arginine to form ornithine and urea. In addition to urea cycle, ARG1 is also implicated in various cellular processes, such as macrophage-mediated cytotoxicity and regulation of immune response. The encoded protein is also involved in allergen challenged lungs, in autoimmune inflammation in the central nervous system and in acute liver injury. Deficiency or mutations in the gene leads to a rare urea cycle disorder, argininemia. |
| Human Arginase 1 ELISA Preparation Products And Raw materials |
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