|
|
| | L-DICENTRINE Basic information |
| Product Name: | L-DICENTRINE | | Synonyms: | (7aR)-6,7,7a,8-Tetrahydro-10,11-dimethoxy-7-methyl-5H-benzo[g]-1,3-benzodioxolo[6,5,4-de]quinoline;Cepharanthine α-base;Eximine;10,11-Dimethoxy-7-methyl-6,7,7A,8-tetrahydro-5H-benzo[G][1,3]benzodioxolo[6,5,4-de]quinoline;5H-Benzo[G]-1,3-benzodioxolo[6,5,4-de]quinoline, 6,7,7A,8-tetrahydro-10,11-dimethoxy-7-methyl-;Inchi=1/C20H21no4/C1-21-5-4-11-7-17-20(25-10-24-17)19-13-9-16(23-3)15(22-2)8-12(13)6-14(21)18(11)19/H7-9,14H,4-6,10H2,1-3h;(R)-(-)-DICENTRINE;L-DICENTRINE | | CAS: | 28832-07-7 | | MF: | C20H21NO4 | | MW: | 339.39 | | EINECS: | | | Product Categories: | Heterocycles;Aromatics;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals | | Mol File: | 28832-07-7.mol |  |
| | L-DICENTRINE Chemical Properties |
| Boiling point | 480.7±45.0 °C(Predicted) | | density | 1.266±0.06 g/cm3 (20 ºC 760 Torr) | | pka | 6.65±0.20(Predicted) |
| | L-DICENTRINE Usage And Synthesis |
| Uses | A natural vascular alpha 1-adrenoceptor antagonist but less prevalent than the D-isomer. It markedly inhibits the contraction of rat stomach muscle strips induced by 5-HT, histamine, K+ and Ca2+ after high K+ depolarization, showing a non-competitive antagonism and could be a potential muscle relaxant. Studies suggest that it has protective effect of on acute myocardial Iichemia and anoxia lesion. |
| | L-DICENTRINE Preparation Products And Raw materials |
|