- 2,4-Thiazolidinedione
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- $65.00 / 1KG
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2024-01-02
- CAS:2295-31-0
- Min. Order: 1KG
- Purity: 0.99
- Supply Ability: 20 tons
- 2,4-Thiazolidinedione
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- $30.00 / 1kg
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2023-11-18
- CAS:2295-31-0
- Min. Order: 1kg
- Purity: 0.99
- Supply Ability: 10 tons
- 2,4-Thiazolidinedione
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- $5.00 / 1KG
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2023-03-31
- CAS:2295-31-0
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: 10000kg
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| | 2,4-Thiazolidinedione Basic information |
| Product Name: | 2,4-Thiazolidinedione | | Synonyms: | 2,4-Thiazolidinedione, 99% 100GR;2,4-Thiazolidinedione, 99% 25GR;thiazolidin-2,4-dione;2,4-Thiazolidinedione technical grade, 90%;2, 4 - Margaret diketone;OTAVA-BB BB7112440002;TIMTEC-BB SBB000047;2,4(3H,5H)-Thiazoledione | | CAS: | 2295-31-0 | | MF: | C3H3NO2S | | MW: | 117.13 | | EINECS: | 218-941-2 | | Product Categories: | Starting Raw Materials & Intermediates;PHARMACEUTICAL INTERMEDIATES;Sulphur Derivatives;Sulfur compounds;blocks;Heterocycles;Thiazoles;Drug Intermediates;(intermedate of rosiglitazone);All Inhibitors;Diabetes;Inhibitors;Ring Systems;Building Blocks;Heterocyclic Building Blocks;bc0001 | | Mol File: | 2295-31-0.mol |  |
| | 2,4-Thiazolidinedione Chemical Properties |
| Melting point | 125-127 °C (lit.) | | Boiling point | 178-179 °C (19 mmHg) | | density | 1.408 (estimate) | | vapor pressure | 0Pa at 25℃ | | refractive index | 1.5130 (estimate) | | Fp | 178-179°C/19mm | | storage temp. | Sealed in dry,Room Temperature | | solubility | DMSO (Slightly), Methanol (Slightly) | | pka | 6.50±0.10(Predicted) | | form | Crystalline Powder | | color | Slightly yellow | | Water Solubility | Soluble in water (30 mg/ml at 3°C), methanol, DMSO, ethanol, and ethyl ether. | | BRN | 110700 | | InChIKey | ZOBPZXTWZATXDG-UHFFFAOYSA-N | | LogP | -0.29 at 25℃ | | CAS DataBase Reference | 2295-31-0(CAS DataBase Reference) | | NIST Chemistry Reference | 2,4-Thiazolidinedione(2295-31-0) | | EPA Substance Registry System | 2,4-Thiazolidinedione (2295-31-0) |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 24/25-36-26 | | WGK Germany | 3 | | RTECS | XJ5775000 | | TSCA | Yes | | HazardClass | IRRITANT | | HS Code | 29341000 |
| | 2,4-Thiazolidinedione Usage And Synthesis |
| Chemical Properties | White to Off-White Powder | | Uses | Inhibitor of enzyme | | Uses | 2,4-Thiazolidinedione may be used in the synthesis of sixteen 5-arylidene-2,4-thiazolidinediones, via ultrasound-promoted aldol condensation reaction. It may be used as starting material for the synthesis of drugs with antihyperglycemic activity. | | Definition | ChEBI: A thiazolidenedione carrying oxo substituents at positions 2 and 4. | | General Description | 2,4-Thiazolidinedione is a well-known peroxisome proliferator-activated receptors (PPAR) activator. Its effect on aging process using kidneys from Fischer 344 rats has been reported. A library of conjugates of 2,4-thiazolidinedione has been synthesized by Knoevenagel condensation followed by reduction using hydrogen gas and Pd/C catalyst. Knoevenagel condensation of various aromatic aldehydes with 2,4-thiazolidinedione in polyethylene glycol-300 has been reported. | | Flammability and Explosibility | Not classified |
| | 2,4-Thiazolidinedione Preparation Products And Raw materials |
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