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Cymoxanil

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Company Name: Capot Chemical Co.,Ltd.
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Products Intro: Product Name:Cymoxanil
CAS:57966-95-7
Purity:98%(Min,GC) Package:100g;1kg;5kg,10kg,25kg,50kg
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Products Intro: CAS:57966-95-7
Company Name: Hubei Jusheng Technology Co.,Ltd.
Tel: 86-18871470254
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Products Intro: Product Name:cymoxanil
CAS:57966-95-7
Purity:99% Package:5KG;1KG
Company Name: Haihang Industry Co.,Ltd
Tel: 86-531-88032799
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Products Intro: CAS:57966-95-7
Package:5KG;1KG
Company Name: Hubei xin bonus chemical co. LTD
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Email: linda@hubeijusheng.com
Products Intro: Product Name:Cymoxanil
CAS:57966-95-7
Purity:0.99 Package:5KG;1KG

Lastest Price from Cymoxanil manufacturers

  • Cymoxanil
  • US $6.60 / KG
  • 2019-12-26
  • CAS:57966-95-7
  • Min. Order: 1KG
  • Purity: 97%-99%
  • Supply Ability: 1kg-1000kg
Cymoxanil Basic information
Description Physical Properties Toxicity Absorption, Distribution and Excretion Uses References
Product Name:Cymoxanil
Synonyms:Cymoxanil-D3;2-CYANO-N-[(ETHYLAMINO)CARBONYL]-2-(METHOXYIMINO)ACETAMIDE;1-(2-cyano-2-methoxyiminoacetyl)-3-ethylurea;PULSAN;RIFLE XG;2-Cyano-2-methoxyimino-N-(ethylcarbamoyl)-acetamide;2-cyano-n-((ethylamino)carbonyl)-2-(methoxyimino)-acetamid;2-cyano-n-(ethylcarbamoyl)-2-(methoxyimino)acetamide
CAS:57966-95-7
MF:C7H10N4O3
MW:198.18
EINECS:261-043-0
Product Categories:FUNGICIDE
Mol File:57966-95-7.mol
Cymoxanil Structure
Cymoxanil Chemical Properties
Melting point 160-161°
Boiling point 335.48°C (rough estimate)
density 1.3841 (rough estimate)
vapor pressure 1.5 x 10-4 Pa (20 °C)
refractive index 1.6700 (estimate)
Fp 100 °C
storage temp. 0-6°C
Water Solubility 890 mg l-1 (pH 5), 780 mg l-1 (pH 7), unstable at pH 9 at 20 °C
pka9.7
form neat
Merck 14,2765
BRN 2214018
CAS DataBase Reference57966-95-7(CAS DataBase Reference)
NIST Chemistry ReferenceAcetamide, 2-cyano-n-[(ethylamino)carbonyl]-2-(methoxyimino)-(57966-95-7)
EPA Substance Registry SystemCymoxanil (57966-95-7)
Safety Information
Hazard Codes Xn;N,N,Xn
Risk Statements 22-43-50/53
Safety Statements 36/37-60-61
RIDADR UN 3077
WGK Germany 3
RTECS AB5957000
HazardClass 9
PackingGroup III
HS Code 29269090
Hazardous Substances Data57966-95-7(Hazardous Substances Data)
ToxicityFor 80% formulations, LD50 orally in male rats: 1425 mg/kg; dermally in male rabbits: >3000 mg/kg. LC50 orally in bobwhite quails, mallard ducks: 2847, >10000 ppm. LC50 (96 hr) in bluegill sunfish, rainbow trout (ppm): 13.5, 18.7 (Klopping, Delp).
MSDS Information
Cymoxanil Usage And Synthesis
DescriptionCymoxanil was first introduced in 1977. It is an acetimide compound used as both a curative and preventative foliar fungicide. In Europe it is being sold for use on grapes, potatoes, tomatoes, hops, sugarbeets and other vegetable crops. Cymoxanil is currently not registered in the U.S. Cymoxanil is a fungicide used on crops including potatoes, tomatoes, and grapes. Cymoxanil is not registered for non-crop use in any country. Cymoxanil's mode of action is as a local systemic. It penetrates rapidly and when inside the plant, it cannot
be washed off by rain. It controls diseases during the incubation period and prevents the appearance of damage on the crop. The fungicide is primarily active on fungi belonging to the Peronosporales order: Phytophthora, Plasmopara, and Peronospora.
Physical Properties

Technical cymoxanil is a peach colored crystalline, odorless solid.

ToxicityTechnical cymoxanil has low acute toxicity. The acute oral LD50 is 960 mg/kg in rats. The acute dermal LD50 is >2,000 mg/kg in rabbits. The 4-hour rat inhalation LC50 is >5.06 mg/L. Minimal transient irritation of the skin and eyes was observed in rabbits. Cymoxanil did not cause skin sensitization in guinea pigs. Cymoxanil should be classified as Toxicity Category III for oral and dermal toxicity and Toxicity Category IV for inhalation toxicity and skin and eye irritation potential.
Absorption, Distribution and Excretion
Cymoxanil is rapidly absorbed and maximum concentrations in the blood and plasma is reached within 4 hours after dosing. Rapid and almost complete elimination of the administered radioactive dose was observed in urine and feces within 48 hours. Excretion is primarily by urine (64-75%), fecal (16-24%) and expired air (< 5%) of the administered dose. There is no significant difference in residue profiles or elimination rates between sexes, dose levels, or single or multiple dosing. No evidence of bioaccumulation was detected. DPX-T3217 is metabolized extensively and only trace level of the administered (14)C-cymoxanil was detected in the urine and feces.
Absorption, Distribution and Excretion

Cymoxanil is rapidly absorbed and maximum concentrations in the blood and plasma is reached within 4 hours after dosing. Rapid and almost complete elimination of the administered radioactive dose was observed in urine and feces within 48 hours. Excretion is primarily by urine (64-75%), fecal (16-24%) and expired air (< 5%) of the administered dose. There is no significant difference in residue profiles or elimination rates between sexes, dose levels, or single or multiple dosing. No evidence of bioaccumulation was detected. DPX-T3217 is metabolized extensively and only trace level of the administered (14)C-cymoxanil was detected in the urine and feces.

Uses

Efficient fungicide

References1. http://pmep.cce.cornell.edu/profiles/extoxnet/carbaryl-dicrotophos/cymoxanil-ext.html
2. https://toxnet.nlm.nih.gov/cgi-bin/sis/search2/r?dbs+hsdb:@term+@rn+@rel+112-31-2
3. http://www.agchemaccess.com/Cymoxanil
Chemical PropertiesA white to peach (pale pink) crystalline solid.
UsesCymoxanil is a fungicide applied as a seed treatment or as a foliar application to the plants to control late blight.
UsesAgricultural fungicide.
UsesCymoxanil is a foliar applied fungicide which provides preventive and curative control of pathogen species of the order Peronosporales (eg. Phytophthora, Plasmopara and Peronospora) in grapes, potatoes, tomatoes, hops, tobacco and cucurbits.
DefinitionChEBI: A member of the class of ureas that is urea in which the two nitrogen atoms are substituted by an ethyl group and a 2-cyano-2-(methoxyimino)acetyl group respectively. A fungicide used to control Peronosporales on a range of crops including vin s, hops and potatoes.
Agricultural UsesFungicide: Cymoxanil is applied as a seed treatment to cut potato seed pieces or as a foliar to control late blight.
Trade nameCURZATE®; DPX 3217®; DPX 3217 M®; DPX-T3217®; EVOLVE®; MZ-CURZATE®; TANOS® Cymoxanil
Contact allergensCymoxanil, an urea derivative, is included (10%) with dithianone (25%) in Aktuan?. It is a fungicide agent, possibly sensitizing agricultural workers
Potential ExposureCymoxanil is a cyanoacetamide oxime fungicide applied as a seed treatment to cut potato seed pieces or as a foliar to control late blight.
Metabolic pathwayCymoxanil is rapidly degraded in neutral to alkaline aqueous solutions and is metabolised extensively in soil, plants and animals. Cymoxanil degradation follows a series of cyclisation and /or hydrolysis reactions to form 5- and 6-membered ring compounds and shorter chain keto acids and amides. In plants and animals, cymoxanil is metabolised to form natural products, especially glycine.
MetabolismAnimals
Radiolabeled cymoxanil is metabolized in the goat to natural products, including fatty acids, glycerol, glycerin, and other amino acids, lactose, and acid-hydrolysable formyl and acetyl groups.
Plants
Rapid degradation to naturally occurring amino acids, particularly to glycine, with subsequent incorporation into constituent sugars, starch, fatty acids, and lignin (6).
Soil
In laboratory soils, DT50 0.75–1.5 d (5 soils, pH range 5.7–7.8, o.m. 0.8–3.5%). In the field, DT50 (bare soil) 0.9–9 d.
ShippingUN3077 Environmentally hazardous substances, solid, n.o.s., Hazard class: 9; Labels: 9-Miscellaneous haz- ardous material, Technical Name Required.
Toxicity evaluationRat oral LD50: 960 mg/kg, mouse oral LD50: 860 mg/kg. Rabbit dermal LD50: >2,000 mg/kg. Mild eye irritant to rabbit (clears at 48 h). Mild, transient dermal irritation to rabbit (clears at 48 h). Inhalation LC50 (4 h) for male and female rats >5.06 mg/L. Nononcogenic and nonteratogenic.
DegradationThe hydrolysis of cymoxanil is pH dependent. It degraded rapidly in alkaline solution at 25 °C with calculated DT50 values at pH 5,7 and 9, of 148 days, 34 hours and 31 minutes, respectively (PM). The principal hydrolysis products at pH 9 were 1-ethyldihydro-dimino-2,4,5(3H)- pyrimidinetrione 5-(O-methyloxime) (2), cyano(methoxyimino)acetic acid (3) and [[(ethylamino)carbonyl]amino]oxoacetic acid (4). Oxalic(5) and aminooxoacetic acid (6) were recovered as minor products. The principal degradation products at pH 7 were compounds 2 and 4. No hydrolytic products at pH 5 exceeded 10% of the applied radioactivity throughout the 30-day incubation (Lawler, 1996).
Photolysis of cymoxanil occurred rapidly at pH 5 when irradiated under a xenon arc light source. The DT50 values of cymoxanil at 25 °C were 1.8 and 148 days, light exposed vs. dark control, respectively. 3-Ethyl-4- (methoxyamino)-2,5-dioxo-4-imidazolidinecarbonitrile(7) and 1-ethyl-imidazolidinetrione 5-(O-methyloxime) (8) were the major degradation products. Compounds 2, 4, 6 and ethylimidazolidinetrione (9) were also present as minor products (Anderson et al., 1993). The hydrolytic degradation and photolytic degradation pathways of cymoxanil are presented in Scheme 1.
Environmental considerationsOral LD50 for bobwhite quail and mallard ducks >2,250 mg/kg. Eight-day dietary LC50 for bobwhite quail and mallard ducks >5,620 mg/kg diet. Fish LC50 (in mg/L at 96 h): rainbow trout 61, bluegill sunfish 29, common carp 91, Zebra fish >47.5 mg/L. Earthworm LC50 (14 d) >2,208 mg/kg soil. Daphnia magna LC50 (48 h) 27 mg/L. Algal growth inhibition LC50 (72 h) 5.2 mg/L. Honeybee contact LD50 >25 μg/bee.
IncompatibilitiesSlowly hydrolyzes in water, releasing ammonia and forming acetate salts. Light sensitive.
Waste DisposalDo not discharge into drains or sewers. Burn in incinerator specifically designed for pes- ticide disposal or dispose as a Hazardous waste in a landfill approved and licensed for the disposal of pesticides. Consult with environmental regulatory agencies for guid- ance on acceptable disposal practices. Ultimate disposal of the chemical must consider: the material’s impact on air quality; potential migration in soil or water; effects on ani- mal, aquatic, and plant life; and conformance with environ- mental and public health regulations.
Cymoxanil Preparation Products And Raw materials
Raw materialsAcetic anhydride-->Urea-->Acetamide-->Cyanoacetic acid-->Ethylurea
Tag:Cymoxanil(57966-95-7) Related Product Information
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