8-BROMOGUANOSINE 3',5'-(CYCLIC) MONOPHOSPHATESODIUM SALT N-HYDRATE manufacturers
- 8-Bromo-cGMP sodium
-
- $55.00 / 5mg
-
2025-07-17
- CAS:51116-01-9
- Min. Order:
- Purity: 99.91%
- Supply Ability: 10g
- 8-Bromo-cGMP sodium
-
- $55.00 / 5mg
-
2025-07-02
- CAS:51116-01-9
- Min. Order:
- Purity: 99.91%
- Supply Ability: 10g
|
| | 8-BROMOGUANOSINE 3',5'-(CYCLIC) MONOPHOSPHATESODIUM SALT N-HYDRATE Basic information |
| Product Name: | 8-BROMOGUANOSINE 3',5'-(CYCLIC) MONOPHOSPHATESODIUM SALT N-HYDRATE | | Synonyms: | 8-bromoguanosine-3’,5’-cyclicmonophosphate(8-br-cgmp),sodiumsalt,;8-bromoguanosine 3:5-cyclic*monophosphate sodiu;8-Bromoguanosine-3,5-cyclomonophosphate sodium salt;Guanosine, 8-bromo-, cyclic 3',5'-(hydrogen phosphate), monosodium salt;8-BROMOGUANOSINE 3':5'-CYCLICMONOPHOSPHA TE SODIUM;8-BROMO-CGMP SODIUM SALT 8-BROMOGUANOSIN E-3',5;GUANOSINE 3',5'-CYCLIC MONOPHOSPHATE, 8-BROMO-, SODIUM SALT;BR-CGMP, NA | | CAS: | 51116-01-9 | | MF: | C10H12BrN5NaO7P | | MW: | 448.1 | | EINECS: | 256-993-8 | | Product Categories: | Cyclic Nucleotide related;Serine/Threonine Kinase Activators;Protein Kinase G (PKG);G Proteins and Cyclic Nucleotides;Cyclic Nucleotides and AnalogsSerine/Threonine Kinase Biology;Cyclic Nucleotide Metabolism | | Mol File: | 51116-01-9.mol |  |
| | 8-BROMOGUANOSINE 3',5'-(CYCLIC) MONOPHOSPHATESODIUM SALT N-HYDRATE Chemical Properties |
| storage temp. | -20°C | | solubility | H2O: 100 mg/mL | | form | powder | | color | White to off-white | | Water Solubility | Soluble to 100 mM in water |
| WGK Germany | 3 | | F | 10-21 | | HS Code | 29349990 |
| | 8-BROMOGUANOSINE 3',5'-(CYCLIC) MONOPHOSPHATESODIUM SALT N-HYDRATE Usage And Synthesis |
| Description | 8-bromo-Cyclic GMP (8-bromo-cGMP) is a cell-permeable analog of cGMP that exhibits greater resistance to hydrolysis by phosphodiesterases than its parent compound. It preferentially activates cGMP-dependent protein kinase. At 1 μM-0.1 mM, 8-bromo-cGMP can inhibit acetylcholine-induced increases in intracellular calcium concentrations. | | Chemical Properties | White powder | | Uses | 8-bromo-cGMP activates cGMP-dependent protein kinase. It can also inhibit acetylcholine-induced increases in intracellular calcium concentrations. | | Definition | ChEBI: Sodium 8-bromo-3',5'-cyclic GMP is an organic sodium salt having 8-bromoguanosine 3',5'-cyclic phosphate as the counterion. A membrane permeable cGMP analogue that activates protein kinase G (PKG). It is 4.3-fold more potent than cGMP in activating PKG1alpha and promotes relaxation of tracheal and vascular smooth muscle tissue in vitro. It has a role as a protein kinase G agonist and a muscle relaxant. It contains an 8-bromo-3',5'-cyclic GMP(1-). | | Biological Activity | Membrane permeable cGMP analog that activates protein kinase G (PKG). 4.3-fold more potent than cGMP in activating PKG1 α and promotes relaxation of tracheal and vascular smooth muscle tissue in vitro . | | storage | Desiccate at -20°C |
| | 8-BROMOGUANOSINE 3',5'-(CYCLIC) MONOPHOSPHATESODIUM SALT N-HYDRATE Preparation Products And Raw materials |
|