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| | (S)-AMPA Basic information |
| Product Name: | (S)-AMPA | | Synonyms: | (S)-A-AMINO-3-HYDROXY-5-METHYL-4-ISOXAZOLEPROPIONIC ACID;(S)-ALPHA-AMINO-3-HYDROXY-5-METHYL-4-ISOXAZOLEPROPIONIC ACID;(S)-ALPHA-AMINO-3-HYDROXY-5-METHYLISOXAZOLE-4-PROPIONIC ACID;(S)-AMPA;(S)-amino-3-hydroxy-5-methylisoxazolepropionic acid;(S)-A-amino-3-hydroxy-5-methylisoxazole -4-propio;(S)-A-AMINO-3-HYDROXY-5-METHYLISOXAZOLE -4-PROPIONI;(s)-α-amino-3-hydroxy-5-methylisoxazole-4-propionic acid | | CAS: | 83643-88-3 | | MF: | C7H10N2O4 | | MW: | 186.17 | | EINECS: | | | Product Categories: | Glutamate receptor;Apoptosis Inducers;Glutamate | | Mol File: | 83643-88-3.mol |  |
| | (S)-AMPA Chemical Properties |
| alpha | D28 -21 ±2° (c = 0.19 in water) | | density | 1.386±0.06 g/cm3(Predicted) | | storage temp. | Store at RT | | form | White to off-white powder. | | pka | 2.15±0.10(Predicted) | | color | White | | Water Solubility | Soluble to 100 mM in water | | CAS DataBase Reference | 83643-88-3(CAS DataBase Reference) |
| | (S)-AMPA Usage And Synthesis |
| Uses | Active enantiomer of AMPA that induces apoptosis in cortical neurons | | Uses | (S)-AMPA has also been used to activate rostromedial tegmental nucleus (RMTg), to study aversive conditioning in relation with cocaine-induced avoidance behaviors in mice. | | Uses | (S)-AMPA is an analogue for AMPA (A611500) a specific agonist for the AMPA receptor which mimics the glutamate receptor. | | General Description | AMPA (α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid) activates excitatory postsynaptic currents (EPSC). | | Biological Activity | Active enantiomer of AMPA (EC 50 = 3.5 μ M). Also available as part of the AMPA Receptor Tocriset™ . | | Biochem/physiol Actions | Active enantiomer of (RS)-AMPA zwitterion. Potent agonist at the AMPA subclass of ionotropic glutamate receptors. | | storage | Room temperature |
| | (S)-AMPA Preparation Products And Raw materials |
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