| Company Name: |
Apollo Scientific Ltd.
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| Tel: |
44 161 406 0505 |
| Email: |
sales@apolloscientific.co.uk |
| Products Intro: |
Product Name:Rat Anti Mouse Interleukin-4
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| Company Name: |
Riedel-de Haen AG
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| Tel: |
800 558-9160 |
| Email: |
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| Products Intro: |
Purity:IgG fraction of antiserum, lyophilized powder Remarks:clone 34019.111, purified immunoglobulin, lyophilized powder
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| Company Name: |
SIGMA-RBI
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| Tel: |
800 736 3690 (Orders) |
| Email: |
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| Products Intro: |
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| Company Name: |
R & D Systems
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| Tel: |
612 379 2956 |
| Email: |
info@rndsystems.com |
| Products Intro: |
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| | ANTI-MOUSE IL-4 Basic information |
| Product Name: | ANTI-MOUSE IL-4 | | Synonyms: | ANTI-MURINE BCDF;ANTI-MURINE B CELL STIMULATING FACTOR;ANTI-MURINE BCGF;ANTI-MURINE BSF-1;ANTI-MURINE IL-4;ANTI-MURINE INTERLEUKIN-4;ANTI-INTERLEUKIN-4;ANTI-INTERLEUKIN-4 (MOUSE) | | CAS: | | | MF: | | | MW: | 0 | | EINECS: | | | Product Categories: | | | Mol File: | Mol File | ![ANTI-MOUSE IL-4 Structure]() |
| | ANTI-MOUSE IL-4 Chemical Properties |
| storage temp. | −20°C | | form | lyophilized powder |
| Hazard Codes | Xn | | Risk Statements | 22 | | WGK Germany | 3 |
| | ANTI-MOUSE IL-4 Usage And Synthesis |
| Uses | Anti-Interleukin-4 antibody may be used for immunoblotting at a working concentration of 1-2 μg/ml. The antibody is suitable for neutralization reactions. | | General Description | Interleukin-4 (IL-4) is a T cell derived chemokine that stimulates the Th2 mediated immune response and proliferation of B cells. The effects of IL-4 are mediated by two types of receptors, type I receptor consisting of IL-4Rα and common γ chain and type II receptor composed of IL-4Rα and IL-13Rα1. The signalling stimulated by IL-4 leads to activation of JAK/STAT6 and IRS-mediated PI3K/Akt pathway. Through these pathways, IL-4 is responsible for endocytic activity of macrophages, chemotaxis of leukocytes in response to inflammation, angiogenesis and regulation of nitric oxide metabolism in macrophages. Anti-tumor effects of IL-4 have been reported in cancers of breast, liver and renal cells
Anti-Interleukin-4 specifically recognizes human interleukin-4 (12-20 kDa). It does not react with mouse IL-4. | | Biochem/physiol Actions | Interleukin-4 (IL-4) is a T cell derived chemokine that stimulates the Th2 mediated immune response and proliferation of B cells. The effects of IL-4 are mediated by two types of receptors, type I receptor consisting of IL-4Rα and common γ chain and type II receptor composed of IL-4Rα and IL-13Rα1. The signaling stimulated by IL-4 leads to activation of JAK/STAT6 and IRS-mediated PI3K/Akt pathway. IL-4 is responsible for endocytic activity of macrophages, chemotaxis of leukocytes in response to inflammation, angiogenesis and regulation of nitric oxide metabolism in macrophages. |
| | ANTI-MOUSE IL-4 Preparation Products And Raw materials |
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