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| | ACETATE KINASE Basic information |
| Product Name: | ACETATE KINASE | | Synonyms: | EC 2.7.2.1;EC: 2.7.2.1;ATP: ACETATE PHOSPHOTRANSFERASE;Kinase (phosphorylating), acetate;ACETATE KINASE FROM ESCHERICHIA COLI;ACETATE KINASE FROM BACILLUSSTEAROTHERMO PHILUS;ACETATE KINASE FROM E. COLI, ~150 U/MG P ROTEIN;ACETATE KINASE FROM METHANOSARCINATHERMO PHILA RECO | | CAS: | 9027-42-3 | | MF: | | | MW: | 0 | | EINECS: | 232-818-0 | | Product Categories: | enzyme | | Mol File: | Mol File | ![ACETATE KINASE Structure]() |
| | ACETATE KINASE Chemical Properties |
| storage temp. | 2-8°C | | form | lyophilized powder |
| Hazard Codes | Xn | | Risk Statements | 22 | | Safety Statements | 24/25 | | RIDADR | UN 1789 8 / PGIII | | WGK Germany | 3 | | F | 10 |
| | ACETATE KINASE Usage And Synthesis |
| Uses | Acetate kinase is used to phosphorylate acetate to acetyl phosphate. Acetate Kinase from Bacillus stearothermophilus has been used to study allosteric activation. [32P]-acetyl phosphate was generated by incubating potassium acetate in the reaction mixture with acetate kinase from Sigma. This [32P]-acetyl phosphate was used to label BldM, BldM D-54N or BldM D-54A loci during the study of the effect of bldM gene on Streptomyces coelicolor development. | | Uses | Acetate kinase is used to phosphorylate acetate to acetyl phosphate. Acetate Kinase from Escherichia coli has been used as part of an ATP-regenerating system to study the kinetics of agonist-stimulated transphosphatidylation . | | General Description | Acetate kinase belongs to acetate and sugar kinase/Hsc70/actin (ASKHA) structural superfamily. It exists as a dimer and has nucleotide binding site in the cleft between N and C-terminal domain. | | Biochem/physiol Actions | Acetate kinase plays an important role in glycolysis. Acetate kinase phosphorylates acetate in the presence of ATP and a divalent cation, which ultimately results in the production of acetyl-CoA. Acetate kinase is also involved in the metabolism of propanoate, pyruvate and taurine. Acetate Kinase from Bacillus stearothermophilus is a thermostable tetramer of identical subunits with molecular weight of 40,000 Da each. The enzyme does not have a -SH group and is composed of 36% β-structure, 21 % α-helix and 43 % unordered structure. |
| | ACETATE KINASE Preparation Products And Raw materials |
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