| Company Name: |
Shanghai Kaiwei Chemical Technology Co., Ltd.
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021-58461859 15821823057 |
| Email: |
service@aiviche.com |
| Products Intro: |
Product Name:2-((3,4-Bis(benzyloxy)benzyl)amino)ethan-1-ol
CAS:500899-98-9
Purity:98% Package:1g;1kg
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| Company Name: |
Shanghai Haohong Pharmaceutical Co., Ltd.
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| Tel: |
400-8210725 4008210725 |
| Email: |
malulu@leyan.com |
| Products Intro: |
Product Name:2-((3,4-Bis(benzyloxy)benzyl)amino)ethan-1-ol
CAS:500899-98-9
Purity:95% Package:1g
|
| Company Name: |
Energy Chemical
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| Tel: |
021-58432009 400-005-6266 |
| Email: |
marketing@energy-chemical.com |
| Products Intro: |
Product Name:2-((3,4-Bis(benzyloxy)benzyl)amino)ethan-1-ol
CAS:500899-98-9
Purity:98% Package:1g Remarks:NULL
|
| Company Name: |
Zhengzhou convergence chemical co., LTD
|
| Tel: |
0371-0371-55153829 18003835034 |
| Email: |
2853979819@qq.com |
| Products Intro: |
Product Name:2-((3,4-Bis(benzyloxy)benzyl)amino)ethan-1-ol
CAS:500899-98-9
Purity:98% Package:g
|
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| | Ethanol, 2-[[[3,4-bis(phenylmethoxy)phenyl]methyl]amino]- Basic information |
| | Ethanol, 2-[[[3,4-bis(phenylmethoxy)phenyl]methyl]amino]- Chemical Properties |
| Boiling point | 550.5±45.0 °C(Predicted) | | density | 1.155±0.06 g/cm3(Predicted) | | storage temp. | 2-8°C | | pka | 14.74±0.10(Predicted) | | form | powder | | color | white to beige | | Water Solubility | H2O: 2mg/mL, clear |
| | Ethanol, 2-[[[3,4-bis(phenylmethoxy)phenyl]methyl]amino]- Usage And Synthesis |
| Biological Activity | XIE62-1004 is a synthetic sequestosome-1 (p62, SQSTM1) ZZ domain ligand th at induces disulfide bond-linked and PB1 domain-dependent p62 self-aggregation, leading to interaction with LC3 on autophagic membranes and p62/cargoes delivery (2.5-10 μM for 6-24 hrs in p62-expressing HeLa cultures). XIE62-1004 treatment (10 μM, 18 hrs) effectively reduces insoluble aggregates of transiently expressed mutant huntingtin (mHTT) constructs in HeLa (GFP-HDQ103) and PC12 (EGFP-HDQ74) trransfectants, as well as in wild-type, but not autophagy defective Atg5-/- MEFs (GFP-HDQ103). |
| | Ethanol, 2-[[[3,4-bis(phenylmethoxy)phenyl]methyl]amino]- Preparation Products And Raw materials |
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