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8-Aminoquinoline Suppliers list
Company Name: Henan Tianfu Chemical Co.,Ltd.
Tel: +86-0371-55170693 +86-19937530512
Products Intro: Product Name:TIANFU CHEM -- 8-Aminoquinoline
Purity:99% Package:25KG;5KG;1KG
Company Name: Hangzhou FandaChem Co.,Ltd.
Tel: +8615858145714
Products Intro: Product Name:8-Aminoquinoline fandachem
Purity:As coa Package:As request Remarks:578-66-5
Tel: +undefined-21-51877795
Products Intro: Product Name:8-aminoquinoline
Purity:98% Package:10MG;50MG;100MG,1G,5G,10G
Company Name: career henan chemical co
Tel: +86-0371-86658258
Products Intro: Product Name:8-Aminoquinoline
Purity:98% Package:1KG;1USD
Company Name: Jinan Finer Chemical Co., Ltd
Tel: +86-531-88989536 +86-15508631887
Products Intro: Product Name:8-Aminoquinoline
Purity:>=99% Package:200KG;5USD

8-Aminoquinoline manufacturers

  • 8-Aminoquinoline
  • 8-Aminoquinoline pictures
  • $0.00 / 1KG
  • 2022-10-13
  • CAS:578-66-5
  • Min. Order: 1KG
  • Purity: 98%
  • Supply Ability: 1Ton
  • 8-Aminoquinoline
  • 8-Aminoquinoline  pictures
  • $1.10 / 1g
  • 2022-03-04
  • CAS:578-66-5
  • Min. Order: 1g
  • Purity: 99.00%
  • Supply Ability: 100 Tons
  • 8-Aminoquinoline
  • 8-Aminoquinoline pictures
  • $10.00 / 1KG
  • 2021-10-29
  • CAS:578-66-5
  • Min. Order: 1000KG
  • Purity: 99.99%
  • Supply Ability: 10000t
8-Aminoquinoline Basic information
Product Name:8-Aminoquinoline
Synonyms:8-amino-quinolin;nc066;Quinoline, 8-amino-;wr6920;TIMTEC-BB SBB004126;ASISCHEM Z74664;AKOS AUF01700;AKOS 91147
Product Categories:Quinolines, Quinazolines and derivatives;Quinoline&Isoquinoline;Quinolines;Aminoquinolines;quinoline
Mol File:578-66-5.mol
8-Aminoquinoline Structure
8-Aminoquinoline Chemical Properties
Melting point 60-65 °C (lit.)
Boiling point 174 °C/26 mmHg (lit.)
density 1.1148 (estimate)
refractive index 1.7080 (estimate)
Fp 174°C/26mm
storage temp. Keep in dark place,Inert atmosphere,Room temperature
form Crystalline Powder
pkapK1: 3.99(+1) (20°C,μ=0.01)
color Green to beige-brown
Water Solubility slightly soluble
Sensitive Air Sensitive
BRN 114474
CAS DataBase Reference578-66-5(CAS DataBase Reference)
NIST Chemistry Reference8-Quinolinamine(578-66-5)
EPA Substance Registry System8-Quinolinamine (578-66-5)
Safety Information
Hazard Codes Xn,Xi
Risk Statements 68-36/37/38-20/21/22-36/38
Safety Statements 36/37/39-26-22-36
WGK Germany 3
RTECS VA9627000
Hazard Note Harmful/Irritant/Air Sensitive
HazardClass IRRITANT
HS Code 29334990
Toxicitymmo-sat 50 mg/plate MUREAV 39,285,77
MSDS Information
8-Quinolinamine English
ACROS English
ALFA English
8-Aminoquinoline Usage And Synthesis
Chemical Propertiesgreen to beige-brown crystalline powder
Uses8-Aminoquinoline is used as pesticide and pharmaceutical intermediate. It has been used in the preparation of base-stabilized terminal borylene complex of osmium. It is also used in the spectrophotometric determination of bivalent palladium.
PreparationSynthesis of 8-aminoquinoline: Under an ice bath, sulfuric acid (2.0 mL) was added onto quinoline (5 mmol, 1.0 equiv) then 65% nitric acid (3.0 equiv) were added dropwise and stirred for 4h at rt. The mixture was poured into the ice water and neutralized with NaOH; and then extracted with dichloromethane. After dried over Na2SO4 and evaporated in vacuo, used next step without purification.
Mixture of nitroquinolines and 5% Pd/C was solved in ethanol and suspension was saturated with hydrogen gas under atmospheric pressure at 40°C until the starting material was consumed. 2 h later, the mixture was filtered and evaporated. The crude product was purified by silica gel column chromatography, eluting with EtOAc in hexanes to yield the desired 8-aminoquinoline is isolated as a brown solid in a yield of 32%.
Obtained as a brown solid (231 mg, 32%); 1H NMR (500 MHz, CDCl3) δ 8.71 – 8.60 (m, 1H), 7.93 (d, J = 8.2 Hz, 1H), 7.29 – 7.16 (m, 2H), 7.02 (d, J = 8.1 Hz, 1H), 6.80 (d, J = 7.4 Hz, 1H), 4.89 (s, 2H).
General Description8-Aminoquinoline fluoresce moderately to weakly in low dielectric media but not in strongly hydrogen-bonding or acidic aqueous media. The reaction of 8-aminoquinoline with chromium (III), manganese (II), iron (II) and (III), cobalt (II), nickel (II), copper (II), zinc (II), cadmium (II) and platinum (II) salts has been studied.
Safety ProfileHuman mutation data reported.When heated to decomposition it emits toxic fumes ofNOx.
Purification Methods8-Aminoquinoline crystallises from EtOH, ligroin, octane or H2O, and complexes with metals. [Beilstein 22 III/IV 4708, 22/10 V 316.]
Tag:8-Aminoquinoline(578-66-5) Related Product Information
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