- cephaeline USP/EP/BP
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- $1.10 / 1g
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2021-08-05
- CAS:483-17-0
- Min. Order: 1g
- Purity: 0.999
- Supply Ability: 100 Tons min
- cephaeline
-
- $1.00 / 1g
-
2021-07-20
- CAS:483-17-0
- Min. Order: 1g
- Purity: 99%
- Supply Ability: 50tons
- cephaeline
-
- $2.00 / 1KG
-
2019-12-29
- CAS:483-17-0
- Min. Order: 1KG
- Purity: ≥98%
- Supply Ability: 20 tons
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| | cephaeline Basic information |
| Product Name: | cephaeline | | Synonyms: | cephaeline;O-Phosphatidyl-ethanolamine;Cefalin;(-)-Cephaelin;(1R)-1-[[(2S,3R,11bS)-3-Ethyl-1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-2H-benzo[a]quinolizin-2-yl]methyl]-1,2,3,4-tetrahydro-7-methoxy-6-isoquinolinol;7',10,11-Trimethoxyemetan-6'-ol;Cepheline;Desmethylemetine | | CAS: | 483-17-0 | | MF: | C28H38N2O4 | | MW: | 466.61 | | EINECS: | 207-591-6 | | Product Categories: | Chiral Reagents;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals | | Mol File: | 483-17-0.mol |  |
| | cephaeline Chemical Properties |
| Melting point | 115-1160C | | alpha | D20 -43.4° (c = 2 in chloroform) | | Boiling point | 569.42°C (rough estimate) | | density | 1.21±0.1 g/cm3 (20 ºC 760 Torr) | | refractive index | 1.5800 (estimate) | | storage temp. | -20°C Freezer | | solubility | Acetonitrile: slightly soluble; Chloroform: slightly soluble; Ethanol: slightly soluble; Methanol: slightly soluble | | form | A crystalline solid | | pka | 9.90±0.40(Predicted) | | Stability: | Hygroscopic |
| RIDADR | 1544 | | HazardClass | 6.1(b) | | PackingGroup | III |
| | cephaeline Usage And Synthesis |
| Chemical Properties | Crystalline Solid | | Uses | Cephaeline occurs in the ground roots ofipecac along with emetine. The Brazilian variety usually contains about 0.5%cephaeline. It is used as an emetic and anti amebic reagent. | | Uses | Has been used as an emetic and expectorant | | Definition | ChEBI: A pyridoisoquinoline comprising emetam having a hydroxy group at the 6'-position and methoxy substituents at the 7'-, 10- and 11-positions. | | Health Hazard | The toxicity of cephaeline is lower than thatof emetine. The toxic effects are cumula tive. Ingestion of high doses may producehypotension, muscle weakness, and gastroin testinal problems, including nausea, vomiting, and diarrhea. |
| | cephaeline Preparation Products And Raw materials |
| Raw materials | 6-Isoquinolinol, 1-[[(2S,3R,11bS)-3-ethyl-1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-2H-benzo[a]quinolizin-2-yl]methyl]-1,2,3,4-tetrahydro-7-methoxy-, (1S)--->Ethanol |
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