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KPS Chemicals And Pharmaceuticals
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Product Name:Acamprosate
CAS:77337-76-9
Purity:98% Package:1 kg,5 kg, 10 kg,25kg and 1 MT
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3-(acetylamino)propanesulphonic acid manufacturers
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| | 3-(acetylamino)propanesulphonic acid Basic information |
| Product Name: | 3-(acetylamino)propanesulphonic acid | | Synonyms: | 3-(acetylamino)propanesulphonic acid;ACAMPROSATE;N-acetylhomotaurine;3-(Acetylamino)-1-propanesulfonic acid;3-Acetylamino-1-propanesulfonic acid;1-Propanesulfonic acid,3-(acetylamino)-;3-(acetylamino)propanesulphonic acid USP/EP/BP | | CAS: | 77337-76-9 | | MF: | C5H11NO4S | | MW: | 181.21 | | EINECS: | 278-667-4 | | Product Categories: | | | Mol File: | 77337-76-9.mol |  |
| | 3-(acetylamino)propanesulphonic acid Chemical Properties |
| | 3-(acetylamino)propanesulphonic acid Usage And Synthesis |
| Originator | Campral,Merck | | Uses | Treatment
of alcohol dependency. | | Definition | ChEBI: An organosulfonic acid that is propane-1-sulfonic acid substituted by an acetylamino group at position 3. | | Manufacturing Process | In a 4 liter flask provided with stirring means, a bromine funnel and a
thermometer, 17.5% sodium hydroxide solution and aminopropanesulfonic
acid (homotaurine) are added.
After complete dissolution, at a temperature of between 25°-40°C, acetic
anhydride are added so as not to exceed a temperature of between 30°-40°C.
The mixture is then maintained at this temperature by heating for at least 1
h.
The solution is then concentrated in vacuum, the residue is redissolved in 2.5
L of distilled water and the mixture is concentrated again. The residue is then
dissolved in 1.6 L of distilled water, filtered, then concentrated almost
completely. Drying is terminated in an oven in vacuum. A colorless crystalline
powder of 3-acetylaminopropanesulfonate of sodium (sodium Nacetylhomotaurinate)
is obtained.
The 3-acetylaminopropanesulfonic acid may be produced by treatment of 3-
acetylaminopropanesulfonate of sodium with hydrochloric acid.
In practice it is usually used as calcium salt. | | Brand name | Campral (Forest). | | Therapeutic Function | Psychotropic |
| | 3-(acetylamino)propanesulphonic acid Preparation Products And Raw materials |
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