O-(2-Aminoethyl)-O-(2-(Boc-amino)ethyl)octaethylene glycol

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O-(2-Aminoethyl)-O-(2-(Boc-amino)ethyl)octaethylene glycol manufacturers

O-(2-Aminoethyl)-O-(2-(Boc-amino)ethyl)octaethylene glycol Basic information
Product Name:O-(2-Aminoethyl)-O-(2-(Boc-amino)ethyl)octaethylene glycol
Synonyms:boc-peg-amine (n=9);O-(2-AMinoethyl )-O`-[2-(Boc-aMino)ethyl ]octaaethylene glycol;Boc-NH-PEG9-CH2CH2NH2;31-Amino-5,8,11,14,17,20,23,26,29-nonaoxa-2-azahentriacontanoic acid 1,1-dimethylethyl ester;5,8,11,14,17,20,23,26,29-Nonaoxa-2-azahentriacontanoicacid, 31-amino-, 1,1-dimethylethyl ester;t-Boc-N-amido-PEG9-Amine;t-boc-N-amido-PEG10-amine;Boc-N-amido-PEG9-Amine
CAS:890091-43-7
MF:C25H52N2O11
MW:556.69
EINECS:
Product Categories:Chemical Biology;Chemical Synthesis;Heterobifunctional PEGs;High Oligomer Purity PEG;Materials Science;PEGylation;Poly(ethylene glycol) and Poly(ethylene oxide);Polymer Science;Polymers;peg
Mol File:890091-43-7.mol
O-(2-Aminoethyl)-O-(2-(Boc-amino)ethyl)octaethylene glycol Structure
O-(2-Aminoethyl)-O-(2-(Boc-amino)ethyl)octaethylene glycol Chemical Properties
Boiling point 609.8±55.0 °C(Predicted)
density 1.082±0.06 g/cm3(Predicted)
storage temp. 2-8°C
solubility Soluble in Water, DMSO, DMF, DCM
form Liquid
pka12.23±0.46(Predicted)
color Colorless to light yellow
InChIInChI=1S/C25H52N2O11/c1-25(2,3)38-24(28)27-5-7-30-9-11-32-13-15-34-17-19-36-21-23-37-22-20-35-18-16-33-14-12-31-10-8-29-6-4-26/h4-23,26H2,1-3H3,(H,27,28)
InChIKeyRTTGVFBQUXJWJG-UHFFFAOYSA-N
SMILESC(OC(C)(C)C)(=O)NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCN
Safety Information
WGK Germany 3
HS Code 2924190090
Storage Class10 - Combustible liquids
MSDS Information
O-(2-Aminoethyl)-O-(2-(Boc-amino)ethyl)octaethylene glycol Usage And Synthesis
Descriptiont-Boc-N-amido-PEG9-amine is a monodisperse PEG reagent containing an amino group and Boc-protected amino group. The hydrophilic PEG spacer increases solubility in aqueous media. The Boc group can be deprotected under mild acidic conditions to form the free amine.
UsesBoc-amido-PEG9-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
General DescriptionOur highly purified mono-protected homobifunctional polyethylene glycols display oligomer purities of more than 90%. This extremely narrow distribution of oligomers ensures homogeneous products in many applications such as conjugation reactions or introduction of solubilizing units or spacers.
reaction suitabilityreagent type: cross-linking reagent
IC 50PEGs
References[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
O-(2-Aminoethyl)-O-(2-(Boc-amino)ethyl)octaethylene glycol Preparation Products And Raw materials
Raw materialsMs-PEG4-azide-->Hexaethylene glycol-->PEG7-Tos-->Amino-PEG9-Amine-->Azido-PEG6-->Tetraethylene glycol p-toluenesulfonate-->1-Azido-3,6,9-trioxaundecane-11-ol-->Di-tert-butyl dicarbonate-->tetraethylene glycol
Tag:O-(2-Aminoethyl)-O-(2-(Boc-amino)ethyl)octaethylene glycol(890091-43-7) Related Product Information
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