Rutaecarpine manufacturers
- Rutaecarpine
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- $500.00 / 1kg
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2024-04-09
- CAS:20575-76-2
- Min. Order: 1kg
- Purity: 98%
- Supply Ability: 1000
- Rutaecarpine
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- $1.00 / 1KG
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2020-02-04
- CAS:20575-76-2
- Min. Order: 1KG
- Purity: 98% HPLC
- Supply Ability: 10 tons
Related articles - Preparation of Myricetin
- Myricetin(MYR) belongs to flavonoids, mainly exists in the stems and leaves of vine tea or the bark and leaves of bayberry.
- Sep 15，2022
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| | Rutaecarpine Basic information |
| Product Name: | Rutaecarpine | | Synonyms: | 3-[6-(dimethylcarbamoylamino)hexyl]-1,1-dimethyl-urea;1,1'-Hexamethylenebis[3,3-dimethylurea];N,N''-1,6-Hexanediylbis[N',N'-dimethylurea];Rutaecarpine;Ai3-51108;Brn 2116874;Nsc 255317;Urea, 1,1'-hexamethylenebis(3,3-dimethyl- | | CAS: | 20575-76-2 | | MF: | C12H26N4O2 | | MW: | 258.36 | | EINECS: | | | Product Categories: | | | Mol File: | 20575-76-2.mol |  |
| | Rutaecarpine Chemical Properties |
| Boiling point | 512.3±33.0 °C(Predicted) | | density | 1.021±0.06 g/cm3(Predicted) | | pka | 13.98±0.46(Predicted) |
| | Rutaecarpine Usage And Synthesis |
| Biological Functions | Rutaecarpine also inhibits accumulation of macrophages and cholesterol in atherosclerotic lesions and increases cholesterol excretion in other animal models. Additionally, rutaecarpine inhibits hypoxia-induced production of ROS and lactate dehydrogenase and suppresses apoptosis in myocardiocytes. In other cellular models, rutaecarpine decreases corticosterone production, potentially through inhibition of cAMP, 3β-hydroxysteroid dehydrogenase, and 11β-hydroxylase activity. | | Biological Activity | Rutaecarpine is an indoloquinazoline alkaloid originally found in Evodia; it exhibits anti-inflammatory, anti-atherosclerotic, cardioprotective, anorexigenic, and anti-obesity activities. Rutaecarpine inhibits COX-2 and also decreases food intake, weight gain, and serum glucose, leptin, and insulin levels in vivo by inhibiting expression of neuropeptide Y and AgRP. | | Mechanism of action | Rutaecarpine also inhibits production of ROS, NO, and iNOS, potentially through inhibition of NADPH oxidase. In macrophages, rutaecarpine inhibits arachidonic acid release and decreases production of prostaglandin E2 (PGE2); in other in vitro models, it inhibits collagen-stimulated formation of thromboxane B2 and inosine monophosphate. |
| | Rutaecarpine Preparation Products And Raw materials |
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