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| | 2,6-Dioxopiperidine-3-ammonium chloride Basic information | | Description |
| Product Name: | 2,6-Dioxopiperidine-3-ammonium chloride | | Synonyms: | 2,6-Dioxopiperidine-3-ammonium chloride;2,6-Piperidinedione, 3-amino-, hydrochloride;Glutamic acid imide hydrochloride;3-Amino-2,6-dioxo-piperidine hydrochloride ,99%;3-AMino-2,6-Piperidinedione HCl;3-AMino-2,6-dioxo-piperidine hydrochloride;2,6-Piperidinedione,3-aMino-, hydrochloride (1:1);3-amino piperdine-2,6-dion hydrochloride | | CAS: | 24666-56-6 | | MF: | C5H9ClN2O2 | | MW: | 164.59016 | | EINECS: | 807-866-6 | | Product Categories: | Pyrrolidines;24666-56-6 | | Mol File: | 24666-56-6.mol |  |
| | 2,6-Dioxopiperidine-3-ammonium chloride Chemical Properties |
| Melting point | 120 °C (approx) | | storage temp. | Inert atmosphere,Room Temperature | | solubility | DMSO (Slightly, Heated), Methanol (Sparingly, Sonicated) | | form | powder | | color | White | | InChI | InChI=1S/C5H8N2O2.ClH/c6-3-1-2-4(8)7-5(3)9;/h3H,1-2,6H2,(H,7,8,9);1H | | InChIKey | YCPULGHBTPQLRH-UHFFFAOYSA-N | | SMILES | C1CC(N)C(=O)NC1=O.Cl |
| | 2,6-Dioxopiperidine-3-ammonium chloride Usage And Synthesis |
| Description | 2,6-Dioxopiperidine-3-ammonium chloride is a reagent for preparing lenalidomide that can induce ubiquitination and degradation of CK1α in del (5q) MDS. It can also be used to prepare phthalimide conjugates that can promote ligand-dependent target protein degradation. Moreover, it is also a metabolite of thalidomide (T338850) that inhibits FGF-induced angiogenesis.
| | Chemical Properties | White crystal | | Uses | 2,6-Dioxopiperidine-3-ammonium chloride can be used as an important intermediate of antineoplastic drug lenalidomide. |
| | 2,6-Dioxopiperidine-3-ammonium chloride Preparation Products And Raw materials |
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