| Company Name: |
TargetMol Chemicals Inc.
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| Tel: |
15002134094 |
| Email: |
marketing@targetmol.cn |
| Products Intro: |
Product Name:Anti-inflammatory agent 11
CAS:63932-07-0
Package:50mg/RMB 13800;25mg/RMB 10600;100mg/RMB 17500
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4-Pyridinecarboxylic acid, 2-[[(phenylmethyl)amino]thioxomethyl]hydrazide manufacturers
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| | 4-Pyridinecarboxylic acid, 2-[[(phenylmethyl)amino]thioxomethyl]hydrazide Basic information |
| | 4-Pyridinecarboxylic acid, 2-[[(phenylmethyl)amino]thioxomethyl]hydrazide Chemical Properties |
| Melting point | 219-222 °C(Solv: ethanol (64-17-5)) | | density | 1.285±0.06 g/cm3(Predicted) | | pka | 8?+-.0.70(Predicted) |
| | 4-Pyridinecarboxylic acid, 2-[[(phenylmethyl)amino]thioxomethyl]hydrazide Usage And Synthesis |
| Uses | Anti-inflammatory agent 11 (compound 16) is a potent antimycobacterial and anti-inflammatory agent. Anti-inflammatory agent 11 inhibits Mtb H37Rv and M299 growth, with MIC50 (minimum inhibitory concentration 50%) of 1.3 and 6.9 μM, respectively. Anti-inflammatory agent 11 inhibits NO through the suppression of iNOS expression, and also inhibited the production of TNF-α and IL-1β. Anti-inflammatory agent 11 can be used for tuberculosis (TB) research[1]. | | References | [1] Calixto SD, et al. Antimycobacterial and anti-inflammatory activities of thiourea derivatives focusing on treatment approaches for severe pulmonary tuberculosis. Bioorg Med Chem. 2022 Jan 1;53:116506. DOI:10.1016/j.bmc.2021.116506 |
| | 4-Pyridinecarboxylic acid, 2-[[(phenylmethyl)amino]thioxomethyl]hydrazide Preparation Products And Raw materials |
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