| Company Name: |
Suzhou Meishi Biotechnology Co., Ltd.
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| Tel: |
1173954148q |
| Email: |
meishipharma@126.com |
| Products Intro: |
Product Name:159776-68-8
CAS:159776-68-8
Purity:99% HPLC Package:1G;5G;10G;100G;1KG;
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| Company Name: |
Shanghai Yifei Biotechnology Co. , Ltd.
|
| Tel: |
021-65675885 18964387627 |
| Email: |
customer_service@efebio.com |
| Products Intro: |
Product Name:Linetastine
CAS:159776-68-8
Purity:99% Package:1mg;5mg;10mg
|
| Company Name: |
TargetMol Chemicals Inc.
|
| Tel: |
15002134094 |
| Email: |
marketing@targetmol.cn |
| Products Intro: |
Product Name:Linetastine
CAS:159776-68-8
Purity:99.55% Package:1mg/RMB 910;5mg/RMB 2230;10mg/RMB 3350
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Linetastine manufacturers
- Linetastine
-
- $78.00 / 1mg
-
2025-11-09
- CAS:159776-68-8
- Min. Order:
- Purity: 99.76%
- Supply Ability: 10g
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| | Linetastine Basic information |
| Product Name: | Linetastine | | Synonyms: | Linetastine;Linetastine [inn];Unii-7U248Z56la;[4-[(1E,3E)-5-[2-(4-benzhydryloxypiperidin-1-yl)ethylamino]-5-oxopenta-1,3-dienyl]-2-methoxyphenyl] ethyl carbonate;Carbonic acid, 4-[(1E,3E)-5-[[2-[4-(diphenylmethoxy)-1-piperidinyl]ethyl]amino]-5-oxo-1,3-pentadien-1-yl]-2-methoxyphenyl ethyl ester | | CAS: | 159776-68-8 | | MF: | C35H40N2O6 | | MW: | 584.7 | | EINECS: | | | Product Categories: | | | Mol File: | 159776-68-8.mol |  |
| | Linetastine Chemical Properties |
| Boiling point | 760.9±60.0 °C(Predicted) | | density | 1.20±0.1 g/cm3(Predicted) | | pka | 14.19±0.46(Predicted) |
| | Linetastine Usage And Synthesis |
| Uses | Linetastine is an orally active and potent 5-Lipoxygenase inhibitor. Linetastine shows antihistamine activity. Linetastine inhibits leukotriene production and antagonizes the effect of histamine. Linetastine inhibits the release of leukotrienes B4 and C4 from calcium ionophore-stimulated human leukocytes[1]. | | in vivo | Linetastine inhibits histamine-induced bronchoconstriction dose-dependently at 1-10 mg/kg (p.o.) in guinea-pigs, and the effect lasts for more than 24 h[1]. | | IC 50 | 5-Lipoxygenase; Histamine Receptor | | References | [1] Shizawa T, et al. 5-Lipoxygenase inhibitory and antihistamine activities of linetastine. Arzneimittelforschung. 1996 Nov;46(11):1072-6. PMID:8955867 |
| | Linetastine Preparation Products And Raw materials |
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