| Company Name: |
Nantong Hanfang Biotechnology Co. , Ltd.
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| Tel: |
hanfangpharma@126.com; 18616537568 |
| Email: |
hanfangpharma@126.com |
| Products Intro: |
Product Name:4-Quinolinecarboxamide, N-[4-(aminosulfonyl)phenyl]-2-(1,3-benzodioxol-5-yl)-
CAS:546105-61-7
Purity:98%+ Package:1g；5g；10g；100g; 1kg
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| Company Name: |
TargetMol Chemicals Inc.
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| Tel: |
15002134094 |
| Email: |
marketing@targetmol.cn |
| Products Intro: |
Product Name:Carbonic anhydrase inhibitor 7
CAS:546105-61-7
Package:50mg/RMB 13800;100mg/RMB 17500;25mg/RMB 10600
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4-Quinolinecarboxamide, N-[4-(aminosulfonyl)phenyl]-2-(1,3-benzodioxol-5-yl)- manufacturers
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| | 4-Quinolinecarboxamide, N-[4-(aminosulfonyl)phenyl]-2-(1,3-benzodioxol-5-yl)- Basic information |
| | 4-Quinolinecarboxamide, N-[4-(aminosulfonyl)phenyl]-2-(1,3-benzodioxol-5-yl)- Chemical Properties |
| density | 1.486±0.06 g/cm3(Predicted) | | pka | 9.81±0.12(Predicted) |
| | 4-Quinolinecarboxamide, N-[4-(aminosulfonyl)phenyl]-2-(1,3-benzodioxol-5-yl)- Usage And Synthesis |
| Uses | Carbonic anhydrase inhibitor 7 (compound 5b) is a potent inhibitor of human carbonic anhydrase (hCA), with Kis of 6.5 nM, 7.1 nM, 72.1 nM, and 255.8 nM for hCA IX, hCA II, hCA XII and hCA I, respectively[1]. | | References | [1] Swain B, et, al. Exploration of 2-phenylquinoline-4-carboxamide linked benzene sulfonamide derivatives as isoform selective inhibitors of transmembrane human carbonic anhydrases. Eur J Med Chem. 2022 Apr 15;234:114247. DOI:10.1016/j.ejmech.2022.114247 |
| | 4-Quinolinecarboxamide, N-[4-(aminosulfonyl)phenyl]-2-(1,3-benzodioxol-5-yl)- Preparation Products And Raw materials |
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