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ETHYLENESULFATE

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ETHYLENESULFATE manufacturers

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ETHYLENESULFATE Basic information
Product Name:ETHYLENESULFATE
Synonyms:glycolsulfate;1,2-ETHYLENE SULFATE;Ethylenesulfate ,98%;NSC 526594;sulfuricacid,cyclicethyleneester;ETHYLENESULFATE;ETHYLENESULPHATE;GLYCOLSULPHATE
CAS:1072-53-3
MF:C2H4O4S
MW:124.12
EINECS:600-809-4
Product Categories:Fine Chemical;Used in organic synthesis of sterically hydroxyethyl synthetic drug intermediates;Biphenyl & Diphenyl ether;Building Blocks;Chemical Synthesis;Heterocyclic Building Blocks;Heterocyclic Compounds;Heterocyclic Building Blocks;Others;S-Containing;3;1072-53-3
Mol File:1072-53-3.mol
ETHYLENESULFATE Structure
ETHYLENESULFATE Chemical Properties
Melting point 95-97 °C (lit.)
Boiling point 231.1±7.0℃ (760 Torr)
density 1.604±0.06 g/cm3 (20 ºC 760 Torr)
vapor pressure 0.91-1.7Pa at 20-25℃
refractive index 1.5090 (estimate)
Fp 93.5±18.2℃
storage temp. 2-8°C
solubility Chloroform, Methanol
form solid
color White to Off-White
InChIInChI=1S/C2H4O4S/c3-7(4)5-1-2-6-7/h1-2H2
InChIKeyZPFAVCIQZKRBGF-UHFFFAOYSA-N
SMILESC1OS(=O)(=O)OC1
LogP-0.45 at 23℃ and pH1.4-1.7
Surface tension66.8mN/m at 1g/L and 20℃
Safety Information
Risk Statements 22
WGK Germany 3
RTECS JH4800000
HS Code 29209085
Storage Class8B - Non-combustible corrosive hazardous materials
Hazard ClassificationsAcute Tox. 4 Oral
Carc. 2
Eye Dam. 1
Skin Corr. 1B
Skin Sens. 1B
MSDS Information
ProviderLanguage
SigmaAldrich English
ETHYLENESULFATE Usage And Synthesis
Chemical PropertiesWhite Solid
Uses1,3,2-Dioxathiolane 2,2-Dioxide is an alkylating agent with carcinogenic activty.
Uses1,3,2-Dioxathiolane 2,2-dioxide may be employed in the preparation of imidazolidinium salts.
Synthesis Cyclic sulfates of 1,2-diols (1,3,2-dioxathiolane 2,2-dioxides) are most easily prepared in a two-step procedure (eq 1). The reaction of a 1,2-diol with Thionyl Chloride leads to a cyclic sulfite, which is then oxidized to the corresponding cyclic sulfate (1). Direct conversion of a 1,2-diol to a cyclic sulfate using Sulfuryl Chloride is generally less efficient.
ETHYLENESULFATE
Toxics Screening LevelThe initial threshold screening level (ITSL) for 1,3,2-dioxathiolane,2,2-dioxide (CAS #1072-53-3) is 0.1 μg/m3 annual averaging time.
PrecautionsThe structural similarity between cyclic sulfates and Dimethyl Sulfate must be recognized. Dimethyl sulfate, and to a lesser extent, ethylene sulfate, are carcinogenic and potent alkylating agents that are toxic by inhalation and ingestion. Cyclic sulfates must, as a result, be treated with extreme care.
References[1] Patent: CN108822073, 2018, A. Location in patent: Paragraph 0017-0028
[2] Patent: CN106187989, 2016, A. Location in patent: Paragraph 0016
[3] Acta Chemica Scandinavica, 1996, vol. 50, # 2, p. 170 - 177
[4] Journal of the Chemical Society, Chemical Communications, 1983, # 23, p. 1392 - 1394
[5] Molecules, 2005, vol. 10, # 9, p. 1169 - 1178
Tag:ETHYLENESULFATE(1072-53-3) Related Product Information
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