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| | Flavanomarein Basic information |
| Product Name: | Flavanomarein | | Synonyms: | TRIHYDROXYFLAVANONE;7-O-GLUCOSYL-4',5',8-TRIHYDROXYFLAVANONE;FLAVANOMAREIN;ISOOKANIN-7-GLUCOSIDE;ISOOKANIN-7-O-GLUCOSIDE;(S)-2-(3,4-dihydroxyphenyl)-7-(beta-D-glucopyranosyloxy)-2,3-dihydro-8-hydroxy-4H-1-benzopyran-4-one;FLAVANOMAREIN WITH HPLC;FLAVANOMAREIN hplc | | CAS: | 577-38-8 | | MF: | C21H22O11 | | MW: | 450.39 | | EINECS: | 209-411-1 | | Product Categories: | reagent;Flavanones | | Mol File: | 577-38-8.mol |  |
| | Flavanomarein Chemical Properties |
| Melting point | 243-246°C | | Boiling point | 818.2±65.0 °C(Predicted) | | density | 1.665±0.06 g/cm3(Predicted) | | pka | 7.58±0.40(Predicted) | | LogP | -1.080 (est) |
| | Flavanomarein Usage And Synthesis |
| Chemical Properties | Flavanomarein, known as isookanin-7-o-glucoside, is a dihydroflavonoid isolated from the ethanolic extract of Coreopsistinctoria and is considered to be one of the active ingredients of the herb with a wide range of pharmacological effects, but there are not many studies on the in vitro and in vivo pharmacokinetics of flavanomarein. | | Uses | Flavanomarein is a predominant flavonoid of Coreopsis tinctoria Nutt with protective effects against diabetic nephropathy. Flavanomarein has good antioxidative, antidiabetic, antihypertensive and anti-hyperlipidemic activities.
Flavanomarein inhibits high glucose-stimulated epithelialmesenchymal transition in HK-2 cells via targeting spleen tyrosine kinase |
| | Flavanomarein Preparation Products And Raw materials |
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