nandinine

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Products Intro: Product Name:Nandinine
CAS:572-76-9
Purity:HPLC>=98% Package:5mg/10
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Products Intro: Product Name:Nandinine
CAS:572-76-9
Purity:99% HPLC Package:20mg;50mg;100mg;1g
nandinine Basic information
Product Name:nandinine
Synonyms:nandinine;(13aS)-5,8,13,13a-Tetrahydro-10-methoxy-6H-benzo[g]-1,3-benzodioxolo[5,6-a]quinolizin-9-ol;6H-Benzo[g]-1,3-benzodioxolo[5,6-a]quinolizin-9-ol, 5,8,13,13a-tetrahydro-10-methoxy-, (13aS)-
CAS:572-76-9
MF:C19H19NO4
MW:325.36
EINECS:
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Mol File:572-76-9.mol
nandinine Structure
nandinine Chemical Properties
Melting point 195-196°
Safety Information
MSDS Information
nandinine Usage And Synthesis
DescriptionEijkman obtained an amorphous compound from the root bark of Nandina domestica L. to which this name was given. It was subsequently obtained crystal_x0002_line by Iwakawa who was also able to separate it into three well-defined phenolic substances, Nandinine, Domesticine and Isodomesticine (q.v.). This alkaloid may be crystallized from EtOH as colourless leaflets which develop a pink colour on exposure to air. With CH2N2 the base yields (+)-Canadine (q.v.). The solution in H2S04 is initially yellow, changing through green to blue.
DefinitionChEBI: (S)-nandinine is a berberine alkaloid that is 5,8,13,13a-tetrahydro-2H,6H-[1,3]dioxolo[4,5-g]isoquinolino[3,2-a]isoquinoline carrying hydroxy and methoxy substituents at positions 9 and 10 respectively. It has a role as an anti-obesity agent and a plant metabolite. It is an organic heteropentacyclic compound, a berberine alkaloid, an aromatic ether, a member of phenols and a tertiary amino compound.
ReferencesEijkman., Rec. trav. Chim., 3, 197 (1884)
Iwakawa.,Mitt. Med. Ges. Tokyo, 24, 15 (1910)
Kitasato., J. Pharm. Soc., Japan, No. 522, 1 (1925)
Kitasato., Acta Phytochem., 3, 177 (1927)
nandinine Preparation Products And Raw materials
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