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Isobutyl chloroformate

Isobutyl chloroformate Suppliers list
Company Name: Mainchem Co., Ltd.
Tel: +86-0592-6210733
Products Intro: Product Name:Isobutyl chloroformate
Company Name: Xiamen AmoyChem Co., Ltd
Tel: +86 592-605 1114
Products Intro: Product Name:isobutylchloroformate
Company Name: Hubei xin bonus chemical co. LTD
Tel: 86-13657291602
Products Intro: Product Name:Isobutyl chloroformate
Purity:0.99 Package:5KG;1KG
Company Name: Changzhou Carman Chemical Co., Ltd.
Tel: 15061933924;18151214939
Products Intro: Product Name:Isobutyl chloroformate
Purity:98% Package:25kgs
Company Name: Chongqing Chemdad Co., Ltd
Tel: +86-13650506873
Products Intro: Product Name:2-methylpropyl chloroformate

Lastest Price from Isobutyl chloroformate manufacturers

  • Isobutyl chloroformate
  • US $1.00 / kg
  • 2019-07-06
  • CAS:543-27-1
  • Min. Order: 1kg
  • Purity: 99%
  • Supply Ability: Customized
Isobutyl chloroformate Basic information
Product Name:Isobutyl chloroformate
Synonyms:2-methyl-1-propylchlorocarbonate;2-Methylpropyl carbonochloridate;2-Methylpropyl chloroformate;2-methylpropylchloroformate;Chlorocarbonic acid isobutyl ester;chlorocarbonicacidisobutylester;Formic acid, chloro-, isobutyl ester;Isobutyl chloridocarbonate
Product Categories:Acid Halides;Building Blocks;TCI-;Carbonyl Compounds;Chemical Synthesis;Organic Building Blocks;Organics;CHLOROFORMATES;Acid Halides;Carbonyl Compounds;Organic Building Blocks
Mol File:543-27-1.mol
Isobutyl chloroformate Structure
Isobutyl chloroformate Chemical Properties
Melting point -80°C
Boiling point 128.8 °C(lit.)
density 1.053 g/mL at 25 °C(lit.)
vapor pressure 0.33 mm Hg ( 20 °C)
refractive index n20/D 1.407(lit.)
Fp 82 °F
storage temp. 2-8°C
solubility benzene: miscible
form Liquid
color Clear
Water Solubility Immiscible with water.
Sensitive Moisture Sensitive
Merck 14,5139
BRN 956590
CAS DataBase Reference543-27-1(CAS DataBase Reference)
NIST Chemistry ReferenceIsobutyl chloroformate(543-27-1)
EPA Substance Registry SystemCarbonochloridic acid, 2-methylpropyl ester(543-27-1)
Safety Information
Hazard Codes T
Risk Statements 10-22-23-34
Safety Statements 26-36/37/39-45
RIDADR UN 3390 6.1/PG 1
WGK Germany 2
HazardClass 6.1
PackingGroup I
HS Code 29159000
ToxicityLD50 orally in Rabbit: 1400 mg/kg
MSDS Information
SigmaAldrich English
ACROS English
ALFA English
Isobutyl chloroformate Usage And Synthesis
Chemical Propertiesclear liquid
Chemical PropertiesA combustible, colorless to light-colored liquid.
UsesPeptide reagent.
General DescriptionA colorless to light-colored liquid. Insoluble in water and denser than water. Very corrosive to skin, eyes, and mucous membranes. Very toxic by ingestion, inhalation and skin absorption. Combustible.
Air & Water ReactionsHighly flammable. Insoluble in water. Reacts with moisture in the air to produce highly corrosive and toxic fumes of hydrogen chloride gas. Decomposes exothermically in water.
Reactivity ProfileIsobutyl chloroformate is incompatible with water, with strong oxidizing agents, alcohols, bases (including amines). May react vigorously or explosively if mixed with diisopropyl ether or other ethers in the presence of trace amounts of metal salts [J. Haz. Mat., 1981, 4, 291].
HazardFlammable. Corrosive.
Health HazardTOXIC; inhalation, ingestion or contact (skin, eyes) with vapors, dusts or substance may cause severe injury, burns or death. Bromoacetates and chloroacetates are extremely irritating/lachrymators. Reaction with water or moist air will release toxic, corrosive or flammable gases. Reaction with water may generate much heat that will increase the concentration of fumes in the air. Fire will produce irritating, corrosive and/or toxic gases. Runoff from fire control or dilution water may be corrosive and/or toxic and cause pollution.
Fire HazardHIGHLY FLAMMABLE: Will be easily ignited by heat, sparks or flames. Vapors form explosive mixtures with air: indoors, outdoors and sewers explosion hazards. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapors may travel to source of ignition and flash back. Substance will react with water (some violently) releasing flammable, toxic or corrosive gases and runoff. Contact with metals may evolve flammable hydrogen gas. Containers may explode when heated or if contaminated with water.
Potential ExposureThis is a high volume chemical with production exceeding 1 million pounds annually in the U.S . No specific use found
ShippingUN2742 Chloroformates, toxic, corrosive, flammable, n.o.s., Hazard class: 6.1; Labels: 6.1—Poison Inhalation Hazard, 8—Corrosive material; 3—Flammable liquid; Technical Name Required, Potential Inhalation Hazard (Special Provision 5). PG II. UN3390 Toxic by inhalation liquid, corrosive, n.o.s. with an LC50 # 1000 mL/m3 and saturated vapor concentration ≥ 10 LC50, Hazard Class: 6.1; Labels: 6.1—Poisonous materials, 8—Corrosive material, Technical Name Required, Inhalation Hazard Zone B
Purification MethodsIt can be dried over CaCl2 and fractionated at atmospheric pressure while keeping moisture out. Its purity can be checked by conversion to the phenyl urethane derivative with PhNCO [Saunders et al. J Am Chem Soc 73 3796 1951.] IR: 1780cm-1 [Thompson & Jameson Spectrochim Acta 13 236 1959, JustusLiebigs Ann Chem 205 227 1880]. [Beilstein 3 IV 26.]
IncompatibilitiesIncompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explosions. Keep away from alkaline materials, strong bases, strong acids, oxoacids, epoxides, alcohols, ethers, amines. Forms explosive mixture with air above flash point (27C). Compounds of the carboxyl group react with all bases, both inorganic and organic (i.e., amines) releasing substantial heat, water and a salt that may be harmful. Incompatible with arsenic compounds (releases hydrogen cyanide gas), diazo compounds, dithiocarbamates, isocyanates, mercaptans, nitrides, and sulfides (releasing heat, toxic and possibly flammable gases), thiosulfates and dithionites (releasing hydrogen sulfate and oxides of sulfur). Decomposes exothermically in water. Reacts with moisture in air to produce highly corrosive and toxic fumes of hydrogen chloride gas
Waste DisposalDisposal of unused product must be undertaken by qualified personnel who are knowledgeable in all applicable regulations and follow all pertinent safety precautions including the use of appropriate protective equipment. For proper handling and disposal, always comply with federal, state, and local regulations.
Isobutyl chloroformate Preparation Products And Raw materials
Preparation ProductsGLY-7-AMINO-4-METHYLCOUMARIN-->isoglutamine-->Cefpiramide acid
Tag:Isobutyl chloroformate(543-27-1) Related Product Information
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