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ANANDAMIDE

ANANDAMIDE Suppliers list
Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Products Intro: Product Name:Anandamide;(5Z,8Z,11Z,14Z)-N-(2-Hydroxyethyl)icosa-5,8,11,14-tetraenamide
CAS:94421-68-8
Purity:98.00% Package:1 mL * 10mM (in DMSO);10 mg;100 mg;2 mg;25 mg;5 mg;50 mg Remarks:REAGENT;FOR LABORATORY USE ONLY
Company Name: Shanghai UCHEM Inc.
Tel: +862156762820 +86-13564624040
Email: sales@myuchem.com
Products Intro: Product Name:Anandamide
CAS:94421-68-8
Purity:0.98 Package:1G;100MG;5MG
Company Name: Dorne Chemical Technology co. LTD
Tel: +86-86-13583358881 +8618560316533
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Products Intro: Product Name:ANANDAMIDE
CAS:94421-68-8
Purity:0.99
Company Name: Zhejiang J&C Biological Technology Co.,Limited
Tel: +1-2135480471 +1-2135480471
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Products Intro: Product Name:ANANDAMIDE
CAS:94421-68-8
Purity:99% Package:1kg;1USD
Company Name: Hong Kong Tiansheng New Material Trading Co., Ltd
Tel: +8617320695765
Email: zxx@hktiansheng.com
Products Intro: Product Name:Anandamide
CAS:94421-68-8
Purity:99% Package:1KG;15.5USD

ANANDAMIDE manufacturers

  • Anandamide
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  • $32.00 / 1kg
  • 2024-01-08
  • CAS:
  • Min. Order: 1kg
  • Purity: 99.50%
  • Supply Ability: 20tons
  • ANANDAMIDE AEA
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  • $0.00 / 1kg
  • 2023-11-14
  • CAS:94421-68-8
  • Min. Order: 1kg
  • Purity: 99%
  • Supply Ability: 50000kg
  • ANANDAMIDE
  • ANANDAMIDE pictures
  • $15.00 / 1kg
  • 2023-07-31
  • CAS:94421-68-8
  • Min. Order: 10kg
  • Purity: 99%
  • Supply Ability: 20tons
ANANDAMIDE Basic information
Product Name:ANANDAMIDE
Synonyms:Arachidonylethanolamide,AEA, Anandamide, Arachidonic acid N-(hydroxyethyl)amide;Anandamide (in Tocrisolve 100);Arachidonoyl Ethanolamide Lipid Maps MS Standard;(5Z,8Z,11Z,14Z)-N-(2-Hydroxyethyl)-5,8,11,14-eicosatetraenamide;ARACHIDONYLETHANOLAMIDE, >=97.0% (TL;11,14-eicosatetraenamide(all-z)-n-(2-hydroxyethyl)-8;14-eicosatetraenamide,n-(2-hydroxyethyl)-(all-z)-11;5,8,11,14-eicosatetraenoylethanolamide
CAS:94421-68-8
MF:C22H37NO2
MW:347.53
EINECS:200-578-6
Product Categories:Cannabinoid receptor;Cannabinoid
Mol File:94421-68-8.mol
ANANDAMIDE Structure
ANANDAMIDE Chemical Properties
Boiling point 522.3±50.0 °C(Predicted)
density 0.92 g/mL at 25 °C (lit.)
Fp 14 °C
storage temp. -20°C
solubility ethanol: soluble
form oil
pka14.48±0.10(Predicted)
color light yellow
Water Solubility 413ug/L(25 ºC)
Stability:Stable for 1 year from date of purchase as supplied. Subject to oxidation – protect from air. Solutions in degassed DMSO or ethanol may be stored under nitrogen or argon at -80°C for up to 1 month.
Safety Information
Hazard Codes F
Risk Statements 11
Safety Statements 24/25-16-7
RIDADR UN 1170 3/PG 2
WGK Germany 3
RTECS JX3842500
MSDS Information
ProviderLanguage
SigmaAldrich English
ANANDAMIDE Usage And Synthesis
DescriptionAnandamide (94421-68-8) is an endogenous cannabinoid receptor agonist.1-3?Ki=89 nM for CB1?and 371 nM for CB2?receptors.
UsesAnandamide is an endogenous cannabinoid and TRPV1 receptor agonist. Findings suggest that endocannabinoids such as anandamide may help cause runner’s high, the feeling of euphoria, reduced anxiety and lessened ability to feel pain associated with exercise.
DefinitionChEBI: An N-(polyunsaturated fatty acyl)ethanolamine resulting from the formal condensation of carboxy group of arachidonic acid with amino group of ethanolamine.
HazardA reproductive hazard.
Biological ActivityEndogenous cannabinoid and vanilloid receptor agonist, in water-soluble emulsion (for details see TocrisolveTM 100). K i values are 89 and 371 nM for CB 1 and CB 2 receptors respectively; EC 50 values are 18, 31 and 27 nM at GPR55, CB 1 and CB 2 respectively; pK i = 5.68 for rVR1. Also blocks TNF- α -induced NF-kB activation via direct inhibition of IKK. Also available as the pure oil dissolved in ethanol (N-(2-Hydroxyethyl)-5Z,8Z,11Z,14Z-eicosatetraenamide ).
Biochem/physiol ActionsAn arachidonic acid derivative that is an endogenous ligand for the CB cannabinoid receptor and for the VR1 vanilloid receptor. Inhibits calcium currents in neuroblastomas and neurons. Activates the MAP kinase signaling pathway. Inhibits proliferation and induces apoptosis of lymphocytes and human breast cancer cells.
Enzyme inhibitorThis lipid neurotransmitter and endocannabinoid receptor ligand (FW = 347.54 g/mol; CAS 94421-68-8), also known as arachidonylethanolamide, inhibits calcium ion currents and activates the MAP kinase signaling pathway. Anandamide is a naturally occurring effector of central and peripheral nervous systems, as mediated by CB1 and CB2 cannabinoid receptors, respectively. (These receptors were originally characterized as binding Δ9 -tetrahydrocannabinol, or THC, marijuana’s major psychoactive ingredient.) Anandamide, 2-arachidonoylglycerol, and congeners (N- oleoylethanolamide and N-palmitoylethanolamide) are lipophilic signalling molecules with multiple physiological roles in learning and memory, neuroinflammation, oxidative stress, neuroprotection and neurogenesis. Anandamide likewise plays a role in regulating uterine implantation of the early-stage embryo (blastocyst). Anandamide synthesis occurs from N- acetylphosphatidylethanolamine by multiple pathways that include phospholipase A2, phospholipase C, and NAPE-hydrolyzing phospholipase D (or NAPE-PLD). Target(s): adenylate cyclase; Na + channels; a7-nicotinic acetylcholine receptor; 5 HT3 receptors; Ca 2+ channels; K+ channels, voltage-gated; acylglycerol lipase, or monoacylglycerol lipase.
storageStore at -20°C
References1) Devane?et al. (1992),?Isolation and structure of a brain constituent that binds to the cannabinoid receptor; Science,258?1946 2) Devane?et al. (1994),?New dawn of cannabinoid pharmacology; Trends Pharmacol.Sci.,?15?40 3) Hillard?et al. (1997),?Biochemistry and pharmacology of arachidonoylethanolamide, a putative endogenous cannabinoid; J. Lipid Res.,?38?2383
ANANDAMIDE Preparation Products And Raw materials
Raw materialsARACHIDONOYL CHLORIDE-->METHYL ARACHIDONATE-->ETHANOLAMINE HYDROCHLORIDE-->Isobutyl chloroformate-->Arachidonic acid
Tag:ANANDAMIDE(94421-68-8) Related Product Information
ANANDAMIDE ANANDAMIDE Arachidonic acid N-(1-OXO-5Z,8Z,11Z,14Z-EICOSATETRAENYL)-L-ALANINE S-1 METHANANDAMIDE ANANDAMIDE, [ETHANOLAMINE 1-3H] ANANDAMIDE-D8 ANANDAMIDE, [ARACHIDONYL-1-14C] ANANDAMIDE PHOSPHATE R(+)-ARACHIDONYL-1'-HYDROXY-2'-PROPYLAMIDE S-2 METHANANDAMIDE CAY10455 NAGLY ARA-S ANANDAMIDE [ARACHIDONYL-5,6,8,9,11,12,14,15-3H],[3H]-Anandamide ARACHIDONYL TRIFLUOROMETHYL KETONE INHIB ITS ANANDAMIDE H ANANDAMIDE, 2'-FLUORO,2'-FLUORO ANANDAMIDE ANANDAMIDE