- Tiamulin
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- $0.00 / 1kg
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2024-03-25
- CAS:55297-95-5
- Min. Order: 1kg
- Purity: 99%
- Supply Ability: 5000kg
- Tiamulin hyclate
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- $10.00 / 1KG
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2023-03-06
- CAS:55297-95-5
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: 10 ton
- tiamulin
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- $100.00 / 1bag
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2022-03-11
- CAS:55297-95-5
- Min. Order: 1bag
- Purity: 99
- Supply Ability: 500
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| | Tiamulin Basic information |
| Product Name: | Tiamulin | | Synonyms: | [[2-(Diethylamino)ethyl]thio]acetic acid [(3aS,10R,9aβ)-6α-ethenyldecahydro-5α-hydroxy-4β,6,9,10-tetramethyl-1-oxo-3aα,9α-propano-3aH-cyclopentacycloocten]-8β-yl ester;[[2-(Diethylamino)ethyl]thio]acetic acid [(3aS,9aβ,10R)-6α-ethenyldecahydro-5α-hydroxy-4β,6,9,10-tetramethyl-1-oxo-3aα,9α-propano-3aH-cyclopentacycloocten]-8β-yl ester;[2-(Diethylamino)ethylthio]acetic acid [(3aS,9aβ,10R)-6α-ethenyldecahydro-5α-hydroxy-4β,6,9,10-tetramethyl-1-oxo-3aα,9α-propano-3aH-cyclopentacycloocten]-8β-yl ester;C12065;Tiamulin (100 mg);,10-tetramethyl-1-oxo-3a,9-propano-3ah-cyclopentacycloocten-8-ylester,(3as-(;14-deoxy-14-((2-diethylaminoethyl-thio)-acetoxy)mutiline;4-beta,5-alpha,6-alpha,8-beta,9-beta,10s*))-3a-alph | | CAS: | 55297-95-5 | | MF: | C28H47NO4S | | MW: | 493.74 | | EINECS: | 259-580-0 | | Product Categories: | | | Mol File: | 55297-95-5.mol |  |
| | Tiamulin Chemical Properties |
| Melting point | 147.5°C | | Boiling point | 563.0±50.0 °C(Predicted) | | density | 1.0160 (rough estimate) | | refractive index | 1.6550 (estimate) | | storage temp. | -20°C Freezer | | solubility | Chloroform (Slightly), Ethanol (Slightly), Methanol (Slightly) | | pka | 14.65±0.70(Predicted) | | color | Colourless | | CAS DataBase Reference | 55297-95-5(CAS DataBase Reference) | | EPA Substance Registry System | Tiamulin (55297-95-5) |
| | Tiamulin Usage And Synthesis |
| Uses | Tiamulin is a derivative of Pleuromutilin. Antibacterial. | | Uses | Tiamulin is a semi–synthetic analogue of pleuromutilin in which the hydroxyacetyl side chain is replaced with a larger diethylaminoethylthioacetyl moiety, providing greater hydrophobicity and an ionisable group for salt formation and greater water solubility. Tiamulin is a potent and highly selective antibiotic active against a range of Gram positive bacteria, with no cross resistance to existing antibiotic classes due to its unique mode of action. Like pleuromutilin, it inhibits protein synthesis by binding to domain V of 23S rRNA. | | Definition | ChEBI: A carbotricyclic compound that is pleuromutilin in which the hydroxyacetate group is replaced by a 2-{[2-(diethylamino)ethyl]sulfanyl}acetate group. An antibacterial drug, tiamulin is used in veterinary medicine (generally as its hydrogen fumarate salt) fo
the treatment of swine dysentery caused by Serpulina hyodysenteriae. | | General Description | Tiamulin has been developed by that company in collaboration with E.R. Squibb & Sons for use against animal infec tions. Tiamulin is used against dysentery and Mycoplasma infections in sheep, swine, cattle, and chickens. | | Safety Profile | Poison by
intramuscular and intravenous routes.
Moderately toxic by ingestion and
subcutaneous routes. When heated to
decomposition it emits toxic fumes of SOx
and NOx. See also MERCAPTANS. | | Synthesis | Tiamulin was synthesized by Sandoz Co. in 1973, starting from pleuromutilin produced by Pleurotus mutilus. | | Veterinary Drugs and Treatments | Tiamulin is approved for use in swine to treat pneumonia caused
by susceptible strains of Haemophilus pleuropneumoniae and swine
dysentery caused by Treponema hyodysenteriae. As a feed additive, it
is used to cause increased weight gain in swine. |
| | Tiamulin Preparation Products And Raw materials |
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