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| | 5-Methyl-2-pyrazinecarboxylic acid Basic information |
| | 5-Methyl-2-pyrazinecarboxylic acid Chemical Properties |
| Melting point | 167-171 °C(lit.) | | Boiling point | 253.51°C (rough estimate) | | density | 1.3471 (rough estimate) | | refractive index | 1.5100 (estimate) | | storage temp. | Keep in dark place,Sealed in dry,Room Temperature | | solubility | DMSO (Slightly), Methanol (Slightly) | | pka | 3.53±0.10(Predicted) | | form | Amorphous Powder | | color | Orange | | BRN | 116005 | | InChI | InChI=1S/C6H6N2O2/c1-4-2-8-5(3-7-4)6(9)10/h2-3H,1H3,(H,9,10) | | InChIKey | RBYJWCRKFLGNDB-UHFFFAOYSA-N | | SMILES | C1(C(O)=O)=NC=C(C)N=C1 | | LogP | -0.254 (est) | | CAS DataBase Reference | 5521-55-1(CAS DataBase Reference) | | NIST Chemistry Reference | 2-Methylpyrazine-5-carboxylic acid(5521-55-1) |
| Hazard Codes | Xi | | Risk Statements | 41-36/37/38 | | Safety Statements | 26-39-36 | | WGK Germany | 1 | | Hazard Note | Irritant | | HS Code | 29339990 |
| | 5-Methyl-2-pyrazinecarboxylic acid Usage And Synthesis |
| Chemical Properties | Pale Brown Powder | | Uses | 5-Methyl-2-pyrazinecarboxylic acid may be used in the preparation of novel europium(III) complexes, (5-methyl-2-pyrazinecarboxylato) (phenanthroline)europium(III). It may be used in the synthesis of Ln-metal organic frameworks (MOFs). | | General Description | 5-Methyl-2-pyrazinecarboxylic acid is a pyrazine derivative. Simultaneous membrane based solvent extraction (MBSE) and membrane based solvent stripping (MBSS) of 5-methyl-2-pyrazine carboxylic acid (MPCA) has been studied. Mechanism of pertraction of MPCA through layered bulk liquid membranes has been studied. MPCA reacts with Ln(NO3)3·6H2O and K4[W(CN)8]·2H2O to form unique three-dimensional network structure which contains open channels. | | Synthesis | 5-Methylpyrazine-2-carboxylic acid is an intermediate of the lipid-lowering drug amoximus. It can be prepared by electrolytic oxidation of 2,5-dimethyl or 2-methyl-5-(substituted) methylpyrazine. | | References | [1] Angewandte Chemie, 1992, vol. 104, # 6, p. 748 - 749
[2] Patent: CN108017586, 2018, A. Location in patent: Paragraph 0016; 0022-0025
[3] Patent: CN103787990, 2016, B. Location in patent: Paragraph 0035; 0036
[4] Organic Preparations and Procedures International, 1991, vol. 23, # 2, p. 188 - 190
[5] Synthesis, 1990, # 3, p. 207 - 208 |
| | 5-Methyl-2-pyrazinecarboxylic acid Preparation Products And Raw materials |
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