- Vitamin K2 MK-7
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- $450.00 / 1Kg/Bag
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2024-04-22
- CAS:2124-57-4
- Min. Order: 1Kg/Bag
- Purity: 99% up, High Density
- Supply Ability: 20 tons
- Menlaquinone 7
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- $0.00 / 1kg
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2024-04-22
- CAS:2124-57-4
- Min. Order: 1kg
- Purity: 99.8%
- Supply Ability: 1000 kg
- Menlaquinone 7
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- $5.00 / 1KG
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2024-04-02
- CAS:2124-57-4
- Min. Order: 1KG
- Purity: 98%
- Supply Ability: g-kg-tons, free sample is available
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| | Menlaquinone 7 Basic information |
| Product Name: | Menlaquinone 7 | | Synonyms: | (all-E)-2-(3,7,11,15,19,23,27-Heptamethyl-2,6,10,14,18,22,26-octacosaheptaenyl)-3-methyl-1,4-naphthalenedione;Menaquinone K7;Vitamin K2(35);Vitamin MK 7;2-[(2E,6E,10E,14E,18E,22E)-3,7,11,15,19,23,27-Heptamethyl-2,6,10,14,18,22,26-octacosaheptenyl]-3-methyl-1,4-naphthalenedione;Menaquinone-7 Standard;Menaquinone 7, Synthetic;Heptamethene naphthene quinone | | CAS: | 2124-57-4 | | MF: | C46H64O2 | | MW: | 649 | | EINECS: | | | Product Categories: | Intermediates & Fine Chemicals;Pharmaceuticals;Aromatics;APIs | | Mol File: | 2124-57-4.mol |  |
| | Menlaquinone 7 Chemical Properties |
| Melting point | 54 °C | | Boiling point | bp0.0002 200° (some dec) | | density | 0.961 | | storage temp. | -20°C | | solubility | Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly) | | form | Solid | | color | Pale Yellow to Yellow | | Stability: | Light and Temperature Sensitive | | InChIKey | RAKQPZMEYJZGPI-LJWNYQGCSA-N | | SMILES | C1(=O)C2=C(C=CC=C2)C(=O)C(C)=C1C/C=C(\C)/CC/C=C(\C)/CC/C=C(\C)/CC/C=C(\C)/CC/C=C(\C)/CC/C=C(\C)/CC/C=C(/C)\C | | LogP | 14.451 (est) |
| | Menlaquinone 7 Usage And Synthesis |
| Description | Menaquinone 7 (MK-7) is a vitamin K2 analog that has been found in a variety of fermented foods. It increases osteocalcin, osteoprotegerin, and RANKL mRNA expression in osteoblastic MC3T3E cells. MK-7 (1 μM) increases alkaline phosphatase activity and calcium content in femoral-metaphyseal tissues isolated from normal and skeletal-unloaded rats. In vivo, MK-7 (100 μg/g diet) inhibits aortic and myocardial calcification and decreases aortic alkaline phosphatase tissue concentrations in a rat model of extraosseous calcification. It also increases trabecular number, bone mineral density, and bone mineral content in a rat model of ovariectomy-induced bone loss. | | Chemical Properties | Light Yellow Crystalline Solid | | Uses | Vitamin (prothrombogenic) | | Uses | Menaquinones are isoprenoid quinones of the naphthalene series and belongs to the K2 Vitamin homologs. Menaquinones were originally discovered as the anti-hemorrhagic factor and now encompasses a vari
ety of physiological processes. Menaquinone 7 belongs to the class of K2-Vitamins homologs. Menaquinone 7 has been identified as the most bioactive cofactor for the carboxylation reaction of Gla-prote
ins such as osteocalcin and matrix-Gla protein, which plays a crucial role in building and maintaining overall bone health. | | Uses | Vitamin K2 (MK-7)-(5,6,7,8-d4,2-methyl-d3) can be used as a stable isotope internal standard for data interpretation in specific biological samples. | | Definition | ChEBI: A menaquinone whose side-chain contains seven isoprene units in an all-trans-configutation. | | General Description | Vitamin K2, also known as menaquinone, is a polyisoprenoid-substituted?napthoquinone. Menaquinone-7 (MK-7) is a subtype of vitamin K2. It is found in animals, soy protein, fermented products and is primarily produced by bacteria.
Vitamin K2 (MK-7)-(5,6,7,8-d4,2-methyl-d3) is a deuterated vitamin K2 wherein C-5, C-6, C-7, C-8, and 2-methyl protons are replaced by deuterium. | | Side effects | Menlaquinone 7 is usually well tolerated and side effects are rare. Mild digestive symptoms, such as nausea, bloating or diarrhoea, may occur with overdose, but these side effects are usually temporary and will subside on their own. There have been some reports of allergic reactions to Vitamin K2 MK7, including skin rashes and breathing difficulties. As Menlaquinone 7 interferes with the action of blood thinners such as warfarin. Therefore, if you are taking blood thinners, be sure to consult your healthcare provider before taking Vitamin K2 MK7 or any other vitamin or supplement.
Therefore, if you are taking blood thinners, be sure to consult your healthcare provider before taking Vitamin K2 MK7 or any other vitamin or supplement. |
| | Menlaquinone 7 Preparation Products And Raw materials |
| Raw materials | Naphthalene, 2-[(2E,6E,10E,14E,18E,22E)-3,7,11,15,19,23,27-heptamethyl-2,6,10,14,18,22,26-octacosaheptaen-1-yl]-1,4-dimethoxy-3-methyl- |
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