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| | BIS(DIETHYLAMINO)CHLOROPHOSPHINE Basic information |
| | BIS(DIETHYLAMINO)CHLOROPHOSPHINE Chemical Properties |
| Boiling point | 55-57 °C0.2 mm Hg(lit.) | | density | 1.002 g/mL at 25 °C(lit.) | | refractive index | n20/D 1.4895(lit.) | | Fp | 214 °F | | solubility | Chloroform (Sparingly) | | form | Liquid | | pka | 3.96±0.70(Predicted) | | color | Clear colorless to light yellow | | Sensitive | Air & Moisture Sensitive | | Stability: | Hygroscopic, Moisture Sensitive | | InChI | InChI=1S/C8H20ClN2P/c1-5-10(6-2)12(9)11(7-3)8-4/h5-8H2,1-4H3 | | InChIKey | JVEHJSIFWIIFHM-UHFFFAOYSA-N | | SMILES | P(N(CC)CC)(N(CC)CC)Cl | | CAS DataBase Reference | 685-83-6(CAS DataBase Reference) |
| Hazard Codes | C | | Risk Statements | 14-34 | | Safety Statements | 23-26-36-36/37/39-45 | | RIDADR | UN 3265 8/PG 2 | | WGK Germany | 3 | | HazardClass | 8 | | PackingGroup | II | | HS Code | 29299090 | | Storage Class | 8A - Combustible corrosive hazardous materials | | Hazard Classifications | Eye Dam. 1
Skin Corr. 1B |
| | BIS(DIETHYLAMINO)CHLOROPHOSPHINE Usage And Synthesis |
| Chemical Properties | Colorless to light yellow liqui | | Uses | Bis(diethylamino)chlorophosphine is an intermediate in synthesizing Toldimfos Sodium (T535270), a cattle drug that can be used to investigate the bovine serum paraoxonase 1 (PON1) activity. | | reaction suitability | reaction type: Buchwald-Hartwig Cross Coupling Reaction
reaction type: Heck Reaction
reaction type: Hiyama Coupling
reaction type: Negishi Coupling
reaction type: Sonogashira Coupling
reaction type: Stille Coupling
reaction type: Suzuki-Miyaura Coupling |
| | BIS(DIETHYLAMINO)CHLOROPHOSPHINE Preparation Products And Raw materials |
| Raw materials | Hexane-->Phosphorus trichloride-->Diethylamine-->2-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl]-1H-isoindole-1,3(2H)-dione-->1,3,2-Oxathiaphosphole, 2-chloro-5-methyl--->BIS(DIETHYLAMINO)-TERT-BUTOXYPHOSPHINE-->1,3,2-Oxazaphospholidine, 2-chloro-3-phenyl--->N-(Chloromethyl)phthalimide-->Trimethylphosphine-->DIETHYLPHOSPHORAMIDOUS DICHLORIDE-->Diethylamine hydrochloride | | Preparation Products | TRIS(DIETHYLAMINO)PHOSPHINE-->Propane, 1-[(trichloromethyl)thio]--->Ethane, [(trichloromethyl)thio]--->P,P′-(9,9-Dimethyl-9H-xanthene-4,5-diyl)bis[N,N,N′,N′-tetraethyl-phosphonous diamide] 97%-->Bis(diethylamino)[(diphenylphosphino)ethynyl]phosphine |
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