Epipodophyllotoxin

Epipodophyllotoxin Suppliers list
Company Name: Shanghai Zheyan Biotech Co., Ltd.
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Products Intro: Product Name:(-)-Epipodophyllotoxin
CAS:4375-07-9
Purity:HPLC>=98% Package:10mg
Company Name: Chengdu Biopurify Phytochemicals Ltd.
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Products Intro: Product Name:(-)-Epipodophyllotoxin
CAS:4375-07-9
Purity:90%~98% HPLC Package:20mg;100mg;500mg;1g Remarks:BP4372
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Products Intro: Product Name:Epipodophyllotoxin
CAS:4375-07-9
Purity:99% Package:100g
Company Name: Dayang Chem (Hangzhou) Co.,Ltd.
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Products Intro: Product Name:Epipodophyllotoxin
CAS:4375-07-9
Purity:0.95&0.99 Package:0.1KG;1KG;1000KG Remarks:Wholesale price
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Products Intro: Product Name:Epipodophyllotoxin
CAS:4375-07-9
Package:100Mg,1g
Epipodophyllotoxin Basic information
Product Name:Epipodophyllotoxin
Synonyms:Eipodophyllotoxin;(-)-Epipodophyllotoxin;(5R)-5,5aα,8aβ,9-Tetrahydro-9α-hydroxy-5β-(3,4,5-trimethoxyphenyl)furo[3',4':6,7]naphtho[2,3-d]-1,3-dioxole-6(8H)-one;(5R)-5,8,8aβ,9-Tetrahydro-9α-hydroxy-5β-(3,4,5-trimethoxyphenyl)furo[3',4':6,7]naphtho[2,3-d]-1,3-dioxole-(5aαH)-one;(5R)-5β-(3,4,5-Trimethoxyphenyl)-7α-(hydroxymethyl)-8α-hydroxy-5,6,7,8-tetrahydronaphtho[2,3-d]-1,3-dioxole-6β-carboxylic acid 6,7-lactone;(5R,5aR,8aR,9S)-5,8,8a,9-Tetrahydro-5-(3,4,5-trimethoxyphenyl)-9-hydroxyfuro[3',4':6,7]naphtho[2,3-d]-1,3-dioxol-6(5aH)-one;Furo[3',4':6,7]naphtho[2,3-d]-1,3-dioxol-6(5aH)-one,5,8,8a,9-tetrahydro-9-hydroxy-5-(3,4,5-trimethoxyphenyl)-, (5R,5aR,8aR,9S)-;Epipodophyllotoxin
CAS:4375-07-9
MF:C22H22O8
MW:414.41
EINECS:
Product Categories:Aromatics, Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals
Mol File:4375-07-9.mol
Epipodophyllotoxin Structure
Epipodophyllotoxin Chemical Properties
Melting point 160.3°C
Boiling point 453.31°C (rough estimate)
density 1.2649 (rough estimate)
refractive index 1.4480 (estimate)
pka13.26±0.40(Predicted)
Safety Information
MSDS Information
Epipodophyllotoxin Usage And Synthesis
UsesEpipodophyllotoxins is a naturally occuring antitumors agent extracted from Mayapple plant.
Anticancer ResearchIt is a lignan compound; podophyllotoxin is isolated from the roots of Podophyllumpeltatum and P. emodi. Teniposide and etoposide are the semisynthetic derivativesof epipodophyllotoxin, and they are used for lymphomas and bronchial and testicularcancers (Shoeb 2006). These compounds break DNA molecules during the G2/Mphase in cell cycle by binding to tubulin and irreversibly inhibiting DNAtopoisomerase II (Balunas and Kinghorn 2005). Podophyllotoxin prevents thebreast cancer cell growth by modifying checkpoint kinase 2 (Chk2) signalingpathway and also induces apoptosis in non-small cell lung cancer by cell cyclearrest, autophagy, and ER stress (Singh et al. 2016b).
Epipodophyllotoxin Preparation Products And Raw materials
Tag:Epipodophyllotoxin(4375-07-9) Related Product Information
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