5-(4-CHLOROPHENYL)-2-FURALDEHYDE manufacturers
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| | 5-(4-CHLOROPHENYL)-2-FURALDEHYDE Basic information |
| | 5-(4-CHLOROPHENYL)-2-FURALDEHYDE Chemical Properties |
| Melting point | 128-131 °C (lit.) | | Boiling point | 350.7±32.0 °C(Predicted) | | density | 1.282±0.06 g/cm3(Predicted) | | storage temp. | under inert gas (nitrogen or Argon) at 2-8°C | | form | Needles | | color | Pale brown | | InChI | 1S/C11H7ClO2/c12-9-3-1-8(2-4-9)11-6-5-10(7-13)14-11/h1-7H | | InChIKey | ROJGJNINTRCMBL-UHFFFAOYSA-N | | SMILES | Clc1ccc(cc1)-c2ccc(C=O)o2 | | CAS DataBase Reference | 34035-03-5(CAS DataBase Reference) |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 26-36-37/39 | | WGK Germany | 3 | | HazardClass | IRRITANT | | HS Code | 29321900 | | Storage Class | 11 - Combustible Solids | | Hazard Classifications | Eye Irrit. 2
Skin Irrit. 2
STOT SE 3 |
| | 5-(4-CHLOROPHENYL)-2-FURALDEHYDE Usage And Synthesis |
| Chemical Properties | Pale brown needles | | Uses | 5-(4-Chlorophenyl)furfural was used as one of the aldehydes in the synthesis of uridine-based library. | | Uses | 5-(4-Chlorophenyl)furfural is a metabolite of Azimilide (A926950, 2 HCl); an oral type III potassium channel blocker agent that blocks both the rapid activating component and the slow activating component of the delayed rectifier potassium current. Both preclinical and clinical studies have demonstrated the efficacy of Azimilide and its safety in the treatment of supraventricular and ventricular tachyarrhythmia. Azimilide is also being studied in a worldwide multicenter trial for prevention of sudden cardiac death in patients after myocardial infarction. | | General Description | 5-(4-Chlorophenyl)furfural is a furfural derivative. | | Synthesis | The target compounds 5-(4-chlorophenyl)-2-furancarboxaldehyde (1-9) were synthesized using 2-furancarboxaldehyde and 4-chloroaniline as starting materials and the reaction was carried out with reference to the methodology reported in the literature [3,13] and the structures were confirmed by appropriate characterization means. | | References | [1] Heterocyclic Communications, 2003, vol. 9, # 6, p. 625 - 628
[2] Synthetic Communications, 2005, vol. 35, # 3, p. 333 - 340
[3] Asian Journal of Chemistry, 2013, vol. 25, # 14, p. 7738 - 7742
[4] Asian Journal of Chemistry, 2017, vol. 29, # 4, p. 735 - 741
[5] Russian Journal of Organic Chemistry, 2009, vol. 45, # 9, p. 1375 - 1381 |
| | 5-(4-CHLOROPHENYL)-2-FURALDEHYDE Preparation Products And Raw materials |
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