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Sigma-Aldrich
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Product Name:1,4-Dideoxy-1,4-imino-D-arabinitol hydrochloride
CAS:100991-92-2
Purity:enzyme inhibitor Package:10MG Remarks:D1542-10MG
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| Company Name: |
Shanghai EFE Biological Technology Co., Ltd.
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021-65675885 18964387627 |
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Product Name:1,4-dideoxy-1,4-imino-D-Arabinitol (hydrochloride)
CAS:100991-92-2
Purity:95% Package:1mg;5mg;10mg
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| Company Name: |
Chengdu Push Bio-Technology Co., Ltd.
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028-85370565-229 18080489829 |
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| Products Intro: |
Product Name:1,4-Dideoxy-1,4-imino-D-arabinitol hydrochloride
CAS:100991-92-2
Purity:95% Package:5mg
|
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| | 1,4-DIDEOXY-1,4-IMINO-D-ARABINITOL HYDROCHLORIDE Basic information |
| Product Name: | 1,4-DIDEOXY-1,4-IMINO-D-ARABINITOL HYDROCHLORIDE | | Synonyms: | 1,4-DIDEOXY-1,4-IMINO-D-ARABINITOL HYDROCHLORIDE;2-Hydroxymethyl-3,4-pyrrolidinediol hydrochloride;(2R,3R,4R)-3,4-Dihydroxy-2-(hydroxymethyl)pyrrolidine hydrochloride;1,4-Dideoxy-1,4-imino-D-arabinitol hydrochloride enzyme inhibitor;3,4-Pyrrolidinediol, 2-(hydroxymethyl)-, hydrochloride, (2R,3R,4R)- | | CAS: | 100991-92-2 | | MF: | C5H12ClNO3 | | MW: | 169.61 | | EINECS: | | | Product Categories: | | | Mol File: | Mol File |  |
| | 1,4-DIDEOXY-1,4-IMINO-D-ARABINITOL HYDROCHLORIDE Chemical Properties |
| Melting point | 110-112 °C(Solv: ethyl ether (60-29-7); methanol (67-56-1)) | | storage temp. | 2-8°C | | solubility | DMSO: 10 mg/ml; PBS (pH 7.2): 1 mg/ml | | form | A crystalline solid |
| | 1,4-DIDEOXY-1,4-IMINO-D-ARABINITOL HYDROCHLORIDE Usage And Synthesis |
| Description | 1,4-dideoxy-1,4-imino-D-Arabinitol (DAB) is an inhibitor of glycogen phosphorylase, a key enzyme in glycogenolysis. It inhibits glycogenolysis in isolated liver cells (IC50 = 1.0 μM) and in homogenates of cerebral cortex and cerebellum (IC50s = 463 and 383 nM, respectively). DAB is used to inhibit glycogenolysis, in liver and in brain, in various animal models. | | Uses | 1,4-Dideoxy-1,4-imino-D-arabinitol hydrochloride has been used as an α-glucosidase (GAA) inhibitor. | | General Description | 1,4-Dideoxy-1,4-imino-D-arabinitol is a naturally occurring pyrrolidine alkaloid. It is found in Arachniodes standishii and Angylocalyx boutiqueanus. | | Biochem/physiol Actions | Inhibitor of glycogen phosphorylase and α-glucosidases. |
| | 1,4-DIDEOXY-1,4-IMINO-D-ARABINITOL HYDROCHLORIDE Preparation Products And Raw materials |
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