- Ethyl 4-piperidinecarboxylate
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- $8.00 / 1KG
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2024-03-29
- CAS:1126-09-6
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: g-kg-tons, free sample is available
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| | Ethyl 4-piperidinecarboxylate Basic information |
| | Ethyl 4-piperidinecarboxylate Chemical Properties |
| Boiling point | 204 °C(lit.) | | density | 1.02 g/mL at 25 °C(lit.) | | vapor pressure | 39.4Pa at 25℃ | | refractive index | n20/D 1.459(lit.) | | Fp | 176 °F | | storage temp. | Keep in dark place,Inert atmosphere,Room temperature | | form | Liquid | | pka | 9.83±0.10(Predicted) | | color | Clear colorless to slightly brown | | Water Solubility | miscible | | BRN | 118419 | | LogP | 1.15 | | CAS DataBase Reference | 1126-09-6(CAS DataBase Reference) | | NIST Chemistry Reference | Ethyl piperidine-4-carboxylate(1126-09-6) |
| | Ethyl 4-piperidinecarboxylate Usage And Synthesis |
| Chemical Properties | clear colorless to slightly brown liquid | | Uses | Reactant for synthesis of:• ;SMN protein modulators1• ;β-aryl and β-amino-substituted aliphatic esters by rhodium catalyzed tandem double bond migration/conjugate addition2• ;Nitroethylenediamines by nucleophilic ring opening of nitroimidazolidinone3• ;RhoA inhibitors for cardiovascular disease therapy4• ;Saccharin derived Mannich bases as antimicrobials and antioxidants5Reactant for one-pot reductive amination and Suzuki-Miyaura cross coupling of formyl aryl and heteroaryl MIDA boronates6 | | Uses | It is used as a reactant for synthesis of SMN protein modulators, β-aryl and β-amino-substituted aliphatic esters by rhodium catalyzed tandem double bond migration/conjugate addition, nitroethylenediamines by nucleophilic ring opening of nitroimidazolidinone. It is also involved in the reactions of RhoA inhibitors for cardiovascular disease therapy and saccharin derived Mannich bases as antimicrobials and antioxidants. It is employed as a reactant for one-pot reductive amination and Suzuki-Miyaura cross coupling of formyl aryl and heteroaryl MIDA boronates. | | Uses | Reactant for synthesis of SMN protein modulators and β-aryl and β-amino-substituted aliphatic esters by rhodium catalyzed tandem double bond migration/conjugate addition. | | Synthesis Reference(s) | Tetrahedron Letters, 23, p. 193, 1982 DOI: 10.1016/S0040-4039(00)86783-0 |
| | Ethyl 4-piperidinecarboxylate Preparation Products And Raw materials |
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