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| | 2-HYDROXYISOQUINOLINE-1,3(2H,4H)-DIONE Basic information |
| Product Name: | 2-HYDROXYISOQUINOLINE-1,3(2H,4H)-DIONE | | Synonyms: | 2-HYDROXYISOQUINOLINE-1,3(2H,4H)-DIONE;2-HYDROXY-1,3(2H,4H)-ISOQUINOLINEDIONE;2-Hydroxy-1,2,3,4-tetrahydroisoquinoline-1,3-dione;1,3(2H,4H)-Isoquinolinedione, 2-hydroxy-;2-hydroxy-4h-isoquinoline-1,3-dione | | CAS: | 6890-08-0 | | MF: | C9H7NO3 | | MW: | 177.16 | | EINECS: | | | Product Categories: | Aromatics;Heterocycles;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals | | Mol File: | 6890-08-0.mol |  |
| | 2-HYDROXYISOQUINOLINE-1,3(2H,4H)-DIONE Chemical Properties |
| Melting point | 197-200°C | | Boiling point | 382.7±45.0 °C(Predicted) | | density | 1.510±0.06 g/cm3(Predicted) | | storage temp. | Inert atmosphere,2-8°C | | solubility | DMSO (Slightly), Methanol (Slightly) | | form | Solid | | pka | 7.65±0.20(Predicted) | | color | Pale Beige to Brown |
| | 2-HYDROXYISOQUINOLINE-1,3(2H,4H)-DIONE Usage And Synthesis |
| Chemical Properties | Brown Solid | | Uses | 2-Hydroxyisoquinoline-1,3(2H,4H)-dione was recently discovered as a scaffold for the inhibition of HIV-1 integrase and the RNase H function of HIV-1 reverse transcriptase. Its interaction with Mg2+ and Mn2+ was investigated using different spectroscopic techniques and it was reported that 2-hydroxyisoquinoline-1,3(2H,4H)-dione forms a 1:1 complex with Mg2+ but a 1:2 complex with Mn2+. Antiviral agent. |
| | 2-HYDROXYISOQUINOLINE-1,3(2H,4H)-DIONE Preparation Products And Raw materials |
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