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| | N-(3-Bromo-4-methylphenyl)-4-(4-pyridinylmethyl)-1-phthalazinamine Basic information |
| Product Name: | N-(3-Bromo-4-methylphenyl)-4-(4-pyridinylmethyl)-1-phthalazinamine | | Synonyms: | N-(3-Bromo-4-methylphenyl)-4-(4-pyridinylmethyl)-1-phthalazinamine;Acc-789;ZK 202650;NVP-ACC-789;ACC-789 (NVP-ACC789);ACC-789; ZK-202650; NVP-ACC-789;ACC789;ACC 789;N-(3-Bromo-4-methylphenyl)-4-(pyridin-4-ylmethyl)phthalazin-1-amine;NVP ACC789,Platelet-derived growth factor receptor,inhibit,ZK 202650,PDGFR,NVPACC789,Inhibitor,ZK-202650,ACC789,NVP-ACC789,VEGFR,ACC 789,NVP-ACC-789,Vascular endothelial growth factor receptor | | CAS: | 300842-64-2 | | MF: | C21H17BrN4 | | MW: | 405.29 | | EINECS: | | | Product Categories: | | | Mol File: | 300842-64-2.mol |  |
| | N-(3-Bromo-4-methylphenyl)-4-(4-pyridinylmethyl)-1-phthalazinamine Chemical Properties |
| Boiling point | 607.7±55.0 °C(Predicted) | | density | 1.441 | | storage temp. | Store at -20°C | | solubility | DMSO:13.0(Max Conc. mg/mL);32.08(Max Conc. mM)
DMF:0.5(Max Conc. mg/mL);1.23(Max Conc. mM)
DMF:PBS (pH 7) (1:10):0.09(Max Conc. mg/mL);0.22(Max Conc. mM)
Ethanol:0.2(Max Conc. mg/mL);0.49(Max Conc. mM) | | form | A crystalline solid | | pka | 5.46±0.10(Predicted) |
| | N-(3-Bromo-4-methylphenyl)-4-(4-pyridinylmethyl)-1-phthalazinamine Usage And Synthesis |
| Uses | NVP-ACC789, is an inhibitor of human VEGFR-1, VEGFR-2 (mouse VEGFR-2), VEGFR-3 and PDGFR-β with IC50s of 0.38, 0.02 (0.23), 0.18, 1.4 μM, respectively. |
| | N-(3-Bromo-4-methylphenyl)-4-(4-pyridinylmethyl)-1-phthalazinamine Preparation Products And Raw materials |
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