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Avatrombopag

Avatrombopag Suppliers list
Company Name: Zison Pharmaceutical (Shandong) Co., Ltd.
Tel: +86-0086-531-88259693 +86-18660188356
Email: maguanglei@zisonpharm.com
Products Intro: Product Name:Avatrombopag Base,Avatrombopag
CAS:570406-98-3
Purity:>99% by HPLC Package:25Kg/Drum;0.00;USD|5Kg/Drum;0.00;USD|1Kg/Drum;0.00;USD
Company Name: Jewim Pharmaceutical (Shandong) Co., Ltd.
Tel: +86-15552509998 +86-15621883869
Email: liutf@jewim.com.cn
Products Intro: Product Name:Avatrombopag
CAS:570406-98-3
Purity:0.99_ Package:5KG;1KG
Company Name: Jiangsu shring Biopharma Co., Ltd.
Tel: +8613372282299
Email: sales@shringchem.com
Products Intro: Product Name:Avatrombopag
CAS:570406-98-3
Purity:99% Package:5KG;1KG Remarks:Avatrombopag
Company Name: Zhejiang ZETian Fine Chemicals Co. LTD
Tel: 18957127338
Email: stella@zetchem.com
Products Intro: Product Name:Avatrombopag (AKR-501)
CAS:570406-98-3
Purity:0.99 Package:5KG;1KG Remarks:Have any requirements, pls contact sales@zetchem.com
Company Name: BOC Sciences
Tel: +1-631-485-4226
Email: inquiry@bocsci.com
Products Intro: Product Name:Avatrombopag
CAS:570406-98-3
Purity:98% Package:100mg Remarks:BOC Sciences also provides custom synthesis services for Avatrombopag.

Avatrombopag manufacturers

  • Avatrombopag
  • Avatrombopag pictures
  • $0.00 / 1kg
  • 2023-04-11
  • CAS:570406-98-3
  • Min. Order: 1kg
  • Purity: 99%
  • Supply Ability: 100kg
  • AKR-501 USP/EP/BP
  • AKR-501 USP/EP/BP pictures
  • $1.10 / 1g
  • 2021-08-05
  • CAS:570406-98-3
  • Min. Order: 1g
  • Purity: 99.9%
  • Supply Ability: 100 Tons min

Related articles

Avatrombopag Basic information
Product Name:Avatrombopag
Synonyms:AVATROMBOPAG;AS 1670542;E 5501;4-Piperidinecarboxylic acid, 1-[3-chloro-5-[[[4-(4-chloro-2-thienyl)-5-(4-cyclohexyl-1-piperazinyl)-2-thiazolyl]amino]carbonyl]-2-pyridinyl]-;Avatrombopag(AS1670542);1-(3-Chloro-5-{[4-(4-chloro-2-thienyl)-5-(4-cyclohexyl-1-piperazinyl)-1,3-thiazol-2-yl]carbamoyl}-2-pyridinyl)-4-piperidinecarboxylic acid;1-[3-Chloro-5-[[[4-(4-chloro-2-thienyl)-5-(4-cyclohexyl-1-piperazinyl)-2-thiazolyl]amino]carbo;1-[3-Chloro-5-[[[4-(4-chloro-2-thienyl)-5-(4-cyclohexyl-1-piperazinyl)-2-thiazolyl]amino]carbonyl]-2-pyridinyl]-4-piperidinecarboxylic acid
CAS:570406-98-3
MF:C29H34Cl2N6O3S2
MW:649.65
EINECS:1312995-182-4
Product Categories:Intermediate;API
Mol File:570406-98-3.mol
Avatrombopag Structure
Avatrombopag Chemical Properties
density 1.440
solubility DMSO:27.33(Max Conc. mg/mL);42.07(Max Conc. mM)
form A crystalline solid
pka3.04±0.70(Predicted)
Safety Information
MSDS Information
Avatrombopag Usage And Synthesis
DescriptionAvatrombopag is a medication that used for certain conditions that lead to thrombocytopenia (low platelets) such as thrombocytopenia associated with chronic liver disease in adults who are to undergo a planned medical or dental procedure.It was the third thrombopoietin receptor agonist approved for the treatment of immune thrombocytopenia and the first approved to treat periprocedural thrombocytopenia in patients with chronic liver disease (thereby providing an alternative to blood transfusions for these patients). Avatrombopag was approved for medical use in the United States in 2018, and in the European Union in 2019.
UsesAvatrombopag is used to treat thrombocytopenia (a low number of platelets [type of blood cell needed for blood clotting]) in people with chronic (ongoing) liver disease. It is also used to treat thrombocytopenia in people with chronic immune thrombocytopenia (ITP; an ongoing condition that may cause unusual bruising or bleeding due to an abnormally low number of platelets in the blood).
Mechanism of actionAvatrombopag is in a class of medications called thrombopoietin (TPO) receptor agonists. It works by causing the body to produce more platelets.
targetTPO receptor
IC 50IC 50 value is 3.3 nM.
Avatrombopag Preparation Products And Raw materials
Raw materials4-(4-Chloro-2-thienyl)-2-thiazolamine
Tag:Avatrombopag(570406-98-3) Related Product Information
Unii-4U07F515lg Eltrombopag Ibopamine Hydrochloride Lusutrombopag Lusutrombopag methyl 3'-amino-2'-hydroxy-[1,1'-biphenyl]-3-carboxylate Avatrombopag maleate 4-(4-chlorothiophen-2-yl)-5-(4-cyclohexylpiperazin-1-yl)thiazol-2-amine