| Company Name: |
Shanghai Ennopharm Co., Ltd.
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| Tel: |
+86 (21) 6435-5022 |
| Email: |
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| Products Intro: |
Product Name:Oxi 4503 Combretastatin A-1 phosphate , CA1P
CAS:288847-34-7
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| Company Name: |
SPIRO PHARMA
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| Tel: |
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| Email: |
eric_feng1954@126.com |
| Products Intro: |
Product Name:OXi-4503
CAS:288847-34-7
Purity:95% -98%HPLC Package:1GR;10GR;50GR;100GR;250GR;500GR;1KG;5KG;10KG;100KG
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| Product Name: | CA1P | | Synonyms: | TetrasodiuM coMbretastatin A1 diphosphate;Tetrasodium A1 Diphosphate;CA1P;Oxi 4503 Combretastatin A-1 phosphate , CA1P;COMBRETASTATIN A-1 PHOSPHATE;CoMbretastatin A1 diphosphate tetrasodiuM salt;OXi-4503 sodium;3-Methoxy-6-[(Z)-2-(3,4,5-trimethoxyphenyl)vinyl]-1,2-benzenediol bis(dihydrogen phosphate) tetrasodium salt | | CAS: | 288847-34-7 | | MF: | C18H23NaO12P2 | | MW: | 516.31 | | EINECS: | | | Product Categories: | | | Mol File: | 288847-34-7.mol |  |
| Description | OXi-4503 is the diphosphate prodrug of the stilbenoid combretastatin A1, originally isolated from the plant Combretum caffrum, with vascular-disrupting and antineoplastic activities. Upon administration, combretastatin A1 diphosphate (CA1P) is dephosphorylated to the active metabolite combretastatin A1 (CA1), which promotes rapid microtubule depolymerization; endothelial cell mitotic arrest and apoptosis, destruction of the tumor vasculature, disruption of tumor blood flow and tumor cell necrosis may ensue. |
| | CA1P Preparation Products And Raw materials |
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