| Company Name: |
J & K SCIENTIFIC LTD.
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| Tel: |
010-82848833 400-666-7788 |
| Email: |
jkinfo@jkchemical.com |
| Products Intro: |
Product Name:Valsartan-d9 (Major)
CAS:1089736-73-1
Package:10Mg,1Mg
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- Valsartan-D9
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- $0.00 / 5mg
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2023-05-27
- CAS:1089736-73-1
- Min. Order: 1mg
- Purity: 96%
- Supply Ability: 50 mg
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| | Valsartan D9 Basic information |
| Product Name: | Valsartan D9 | | Synonyms: | L-Valine, N-(1-oxopentyl-d9)-N-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]Methyl]-;ACWBQPMHZXGDFX-KDDXQTGLSA-N;(2S)-3-methyl-2-[2,2,3,3,4,4,5,5,5-nonadeuteriopentanoyl-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]amino]butanoic acid;rac-Valsartan D9;[2H9]-Valsartan (mixture);[2H9]-Valsartan;VALSARTAN-D9 (D7-D9 MIXTURE);Valsartan D9Q: What is
Valsartan D9 Q: What is the CAS Number of
Valsartan D9 Q: What is the storage condition of
Valsartan D9 Q: What are the applications of
Valsartan D9 | | CAS: | 1089736-73-1 | | MF: | C24H29N5O3 | | MW: | 435.53 | | EINECS: | | | Product Categories: | | | Mol File: | 1089736-73-1.mol |  |
| | Valsartan D9 Chemical Properties |
| storage temp. | Store at -20°C | | solubility | DMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: 30 mg/ml | | form | A solid |
| | Valsartan D9 Usage And Synthesis |
| Chemical Properties | White Solid | | Uses | An isotopically labelled version of Valsartan (V095750), a nonpeptide angiotensin II AT1-receptor antagonist. Antihypertensive. | | Biological Activity | Valsartan-d9 is intended for use as an internal standard for the quantification of valsartan by GC- or LC-MS. Valsartan is a nonpeptide antagonist of the angiotensin II type 1 (AT1) receptor (IC50 = 2.7 nM). It is 20,000-fold selective for AT1 over AT2 and, unlike some other AT receptor antagonists, does not alter peroxisome proliferator-activated receptor γ (PPARγ) activity in vitro. In vivo, valsartan (30 mg/kg) increases cardiac output and reduces left ventricular fibrosis in a model of heart failure with reduced ejection fraction in mice with streptozotocin-induced diabetes. Formulations containing valsartan have been used in the treatment of hypertension and heart failure. |
| | Valsartan D9 Preparation Products And Raw materials |
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