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(S)-(+)-Glycidyl Phthalimide

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Company Name: Shanghai Rochi Pharmaceutical Co.,Ltd.
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Products Intro: Product Name:(s)-(+)-n-(2,3-epoxypropyl)phthalimide
CAS:161596-47-0
Purity:99%min Package:1kg 5kg 10kg 25kg
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Products Intro: Product Name:(S)-(+)-GLYCIDYL PHTHALIMIDE
CAS:161596-47-0
Purity:NTL 99％ HPLC;IH Package:25Kg/Drum|10Kg/Drum|5Kg/Drum
Company Name: Beijing Mediking Biopharm Co., Ltd
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Products Intro: Product Name:(S)-(+)-Glycidyl Phthalimide
CAS:161596-47-0
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Products Intro: Product Name:(S)-(+)-GLYCIDYL PHTHALIMIDE
CAS:161596-47-0
Purity:99% Package:1kg;150USD
Company Name: Anhui Ruihan Technology Co., Ltd
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Products Intro: Product Name:(S)-N-Glycidylphthalimide
CAS:161596-47-0
Purity:99% Package:1kg;30USD

(S)-(+)-Glycidyl Phthalimide manufacturers

  • (S)-(+)-Glycidyl Phthalimide
  • (S)-(+)-Glycidyl Phthalimide pictures
  • $8.00 / 1kg
  • 2024-04-23
  • CAS:161596-47-0
  • Min. Order: 1kg
  • Purity: 99%
  • Supply Ability: g-kg-tons, free sample is available
(S)-(+)-Glycidyl Phthalimide Basic information
Product Name:(S)-(+)-Glycidyl Phthalimide
Synonyms:(S)-(+)-GLYCIDYL PHTHALIMIDE;(S)-GLYCIDYL PHTHALIMIDE;2-[[(2S)-oxiran-2-yl]methyl]isoindole-1,3-dione;Rivaroxaban Impurity 39;2-((2S)-OXIRANYLMETHYL)-1H-ISOINDOLE-1,3(2H)-DIONE;(S)-(+)-N-(2,3-Epoxypropyl)phthalimide;2-[(2S)-oxiran-2-ylmethyl]-1H-isoindole-1,3(2H)-dione;Rivaroxaban Intermediate 2
CAS:161596-47-0
MF:C11H9NO3
MW:203.19
EINECS:454-720-9
Product Categories:Oxiranes;Simple 3-Membered Ring Compounds;Intermediate of Rivaroxaban;N-Substituted Maleimides, Succinimides & Phthalimides;N-Substituted Phthalimides;bc0001
Mol File:161596-47-0.mol
(S)-(+)-Glycidyl Phthalimide Structure
(S)-(+)-Glycidyl Phthalimide Chemical Properties
Melting point 102 °C
Boiling point 347.4±15.0 °C(Predicted)
density 1.446±0.06 g/cm3(Predicted)
vapor pressure 0.001-2.17Pa at 25-90.25℃
refractive index 10 ° (C=2.2, CHCl3)
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
solubility Chloroform (Slightly), Ethyl Acetate (Slightly)
pka-2.24±0.20(Predicted)
form Solid
color White
InChIInChI=1S/C11H9NO3/c13-10-8-3-1-2-4-9(8)11(14)12(10)5-7-6-15-7/h1-4,7H,5-6H2/t7-/m0/s1
InChIKeyDUILGEYLVHGSEE-ZETCQYMHSA-N
SMILESC1(=O)C2=C(C=CC=C2)C(=O)N1C[C@H]1CO1
LogP1.2 at 40℃
Safety Information
Hazard Codes Xi
Risk Statements 41
Safety Statements 26-39
WGK Germany 2
HS Code 29252900
MSDS Information
(S)-(+)-Glycidyl Phthalimide Usage And Synthesis
Chemical PropertiesWhite powder
Uses(S)-(+)-Glycidyl Phthalimide is a phthalimide derivative used as an intermediate in the preparation of the antibiotic Linezolid (L466500). It is also a key intermediate of rivaroxaban.
SynthesisPhthalimide and (S)-1-substituent propylene oxide are used as raw materials, a reaction occurs under the action of a catalyst to generate 2-((S)-3-substituent-2-hydroxypropyl isodihydroindole-1,3-dione, and finally (S)-glycidyl phthalimide is generated by means of a ring-closure reaction.
(S)-( )-GLYCIDYL PHTHALIMIDE
(S)-(+)-Glycidyl Phthalimide Preparation Products And Raw materials
Preparation Products2-[(2R)-2-Hydroxy-3-[[4-(3-oxo-4-Morpho linyl)phenyl]aMino]propyl]-1H-isoindole-1 ,3(2H)-dione
Tag:(S)-(+)-Glycidyl Phthalimide(161596-47-0) Related Product Information
N-(Chloromethyl)phthalimide 4-(4-AMINOPHENYL)MORPHOLIN-3-ONE Rivaroxaban Impurity 34 1,2-Cyclohexanedione (S)-(+)-Epichlorohydrin 4-(4-NITROPHENYL)MORPHOLIN-3-ONE 4-[4-(N-(3-chloro-(2R)-2-hydroxy-1-propyl)aMino)phenyl]Morpholin-3-one (S)-4-(4-(5-(Aminomethyl)-2-oxooxazolidin-3-yl)phenyl)morpholin-3-one.HCl 5-CHLOROTHIOPHENE-2-CARBONYL CHLORIDE Ethyl (R)-(-)-4-cyano-3-hydroxybutyate 3-MORPHOLINONE, 4-[4-[(5S)-5-(AMINOMETHYL)-2-OXO-3-OXAZOLIDINYL]PHENYL]- 5-Chloro-2-thiophenecarboxylic Acid m-(Trifluoromethyl)phenylacetic acid 2-[(2R)-2-Hydroxy-3-[[4-(3-oxo-4-Morpho linyl)phenyl]aMino]propyl]-1H-isoindole-1 ,3(2H)-dione Rivaroxaban Impurity 43 Rivaroxaban iMpurity 5 AcetaMide, N-[[(5S)-2-oxo-3-[4-(3-oxo-4-Morpholinyl)phenyl]-5-oxazolidinyl]Methyl]- Rivaroxaban Impurity 38