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Madecassic acid

Madecassic acid Suppliers list
Company Name: Hebei Mojin Biotechnology Co., Ltd
Tel: +8613288715578
Email: sales@hbmojin.com
Products Intro: Product Name:Madecassic acid
CAS:18449-41-7
Purity:99% Package:25KG
Company Name: Shaanxi Haibo Biotechnology Co., Ltd
Tel: +86-02963020060 +86-18629295024
Email: hibo06@xaltbio.com
Products Intro: Product Name:Madecassic acid
CAS:18449-41-7
Purity:99% Package:25kg Remarks:White powder
Company Name: Chongqing Zhihe Biopharmaceutical Co., Ltd.
Tel: +86-18580541567 +86-17782035140
Email: sales@zhswyy.com
Products Intro: Product Name:Madecassic acid
CAS:18449-41-7
Purity:>=98%HPLC Package:1kg;|5kg;|25kg
Company Name: Shanghai Zheyan Biotech Co., Ltd.
Tel: 18017610038
Email: zheyansh@163.com
Products Intro: Product Name:Madecassic acid
CAS:18449-41-7
Purity:HPLC>=98% Package:20mg
Company Name: career henan chemical co
Tel: +86-0371-86658258
Email: sales@coreychem.com
Products Intro: Product Name:Madecassic acid
CAS:18449-41-7
Purity:98% Package:1KG;2USD

Madecassic acid manufacturers

  • Madecassic acid
  • Madecassic acid pictures
  • $0.00 / 1kg
  • 2024-03-29
  • CAS:18449-41-7
  • Min. Order: 0.10000000149011612kg
  • Purity: ≥98%HPLC
  • Supply Ability: 20tons
  • Madecassic acid
  • Madecassic acid pictures
  • $33.72 / 1kg
  • 2023-12-05
  • CAS:18449-41-7
  • Min. Order: 1kg
  • Purity: 99%
  • Supply Ability: 10000kg
  • Hydroxy asiaticoside
  • Hydroxy asiaticoside pictures
  • $33.73 / 1kg
  • 2023-12-05
  • CAS:18449-41-7
  • Min. Order: 1kg
  • Purity: 99%
  • Supply Ability: 10000kg
Madecassic acid Basic information
Product Name:Madecassic acid
Synonyms:(2alpha,3beta,4alpha,6beta)-2,3,6,23-tetrahydroxy-urs-12-en-28-oic acid;MADECASSIC ACID;Urs-12-en-28-oic acid, 2,3,6,23-tetrahydroxy-, (2.alpha.,3.beta.,4.alpha.,6.beta.)-;(1S,2R,4aS,6aS,6aS,6bR,8R,8aR,9R,10R,11R,12aR,14bR)-8,10,11-trihydroxy -9-(hydroxymethyl)-1,2,6a,6b,9,12a-hexamethyl-2,3,4,5,6,6a,7,8,8a,10,1 1,12,13,14b-tetradecahydro-1H-picene-4a-carboxylic acid;Hydroxy asiaticoside;MADECASSIC ACID(P);6BETA-HYDROXYASIATIC ACID;2α,3β,6β,23-Tetrahydroxyurs-12-en-28-oic acid
CAS:18449-41-7
MF:C30H48O6
MW:504.71
EINECS:240-851-7
Product Categories:Inhibitors;Cofactor;chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;Miscellaneous Natural Products;The group of Asiaticoside
Mol File:18449-41-7.mol
Madecassic acid Structure
Madecassic acid Chemical Properties
Melting point 270°C (dec.)
Boiling point 641.7±55.0 °C(Predicted)
density 1.23±0.1 g/cm3(Predicted)
storage temp. 2-8°C
solubility DMSO (Sparingly), Methanol (Slightly, Heated)
pka4.63±0.70(Predicted)
form Solid
color White to Pale Red
InChIKeyPRAUVHZJPXOEIF-MRQYELSVNA-N
LogP4.321 (est)
Safety Information
Hazard Codes Xi
Safety Statements 24/25
HS Code 29389090
MSDS Information
Madecassic acid Usage And Synthesis
DescriptionMadecassic acid is a triterpenoid that has been found in C. asiatica and has diverse biological activities. It inhibits LPS-induced production of nitric oxide (NO), prostaglandin E2 (PGE2; ), TNF-α, IL-1β, and IL-6 in RAW 264.7 macrophages when used at a concentration of 150 μg/ml. Madecassic acid (0.05 and 0.1% in the diet) decreases plasma levels of fibrinogenin and triglycerides, as well as heart and kidney levels of reactive oxygen species (ROS), in a mouse model of diabetes induced by streptozotocin (STZ; ). It decreases tumor growth in a CT26 murine colon cancer model in a dose-dependent manner.
Chemical PropertiesWhite powder
UsesMadecassic Acid is a terpenoid with an ursane skeleton isolated from Centella asiatica. Madecassic Acid displays anti-inflammatory properties as a result of iNOS, COX-2, TNF-alpha, IL-1beta, and IL-6 inhibition via the downregulation of NF-kappaB activation in RAW 264.7 macrophage cells. Madecassic Acid is found in cosmetic products due to its skin-protective activities.
Useswound healing
UsesMadecassic Acid is a terpenoid with an ursane skeleton isolated from Centella asiatica. Madecassic Acid displays anti-inflammatory properties as a result of iNOS, COX-2, TNF-alpha, IL-1beta, and IL-6 inhibition via the downregulation of NF-kappaB activation in RAW 264.7 macrophage cells. Madecassic Acid is found in cosmetic products due to its skin-protective activities.
DefinitionChEBI: A pentacyclic triterpenoid that is ursane substituted by a carboxy group at position 28 and hydroxy groups at positions 2, 3, 6 and 23 (the 2alpha,3beta,6beta stereoisomer).
Madecassic acid Preparation Products And Raw materials
Raw materialsUrs-12-en-28-oic acid, 2,3,6,23-tetrahydroxy-, methyl ester, (2α,3β,4α,6β)-
Tag:Madecassic acid(18449-41-7) Related Product Information
Ethyl 2-(Chlorosulfonyl)acetate ORIENTIN AURANTIO-OBTUSIN CALYCOSIN Stearic acid Centella asiatica extract Asiaticoside Citric acid Folic acid Ascoric Acid Asiatic acid 3,3,5,5-TETRAMETHYLCYCLOHEXANOL Madecassic acid Centella asiatica whole plant MADECASSIC ACID(SECONDARY STANDARD) MADECASSIC ACID(SH) MADECASSIC ACID 95% MADECASSIC ACID(PRIMARY STANDARD)