| Company Name: |
EMMX Biotechnology LLC
|
| Tel: |
888-539-0666 |
| Email: |
info@emmx.com |
| Products Intro: |
Product Name:TC-I 15
CAS:916734-43-5
Purity:98% HPLC Package:5mg;10mg;25mg;50mg;100mg;250mg;500mg;1g
|
| Company Name: |
MedBioPharmaceutical Technology Inc
|
| Tel: |
021-69568360 18916172912 |
| Email: |
order@med-bio.cn |
| Products Intro: |
Product Name:TC-I 15
CAS:916734-43-5
Purity:98% Package:50mg; 10mg Remarks:Medbio
|
TC-I 15 manufacturers
- TC-I 15
-
- $0.00 / 10mg
-
2025-07-20
- CAS:916734-43-5
- Min. Order:
- Purity:
- Supply Ability: 10g
|
| | TC-I 15 Basic information |
| Product Name: | TC-I 15 | | Synonyms: | TC-I 15;XKLHCUGVLCGKKX-RBUKOAKNSA-N;N-[[(4R)-5,5-Dimethyl-3-(phenylsulfonyl)-4-thiazolidinyl]carbonyl]-3-[[[(phenylmethyl)amino]carbonyl]amino]-L-alanine;L-Alanine, N-[[(4R)-5,5-dimethyl-3-(phenylsulfonyl)-4-thiazolidinyl]carbonyl]-3-[[[(phenylmethyl)amino]carbonyl]amino]-;TCI 15,TC I 15 | | CAS: | 916734-43-5 | | MF: | C23H28N4O6S2 | | MW: | 520.62 | | EINECS: | | | Product Categories: | | | Mol File: | 916734-43-5.mol |  |
| | TC-I 15 Chemical Properties |
| storage temp. | Store at -20°C | | solubility | Soluble to 100 mM in DMSO and to 25 mM in 1.1eq. NaOH | | form | Powder | | color | White to off-white |
| | TC-I 15 Usage And Synthesis |
| Uses | TC-I 15 is an inhibitor of integrin α2β1, a collagen receptor. TC-I 15 has shown to prevent pathological thrombus formation . | | in vivo | TC I-15 (10 μg; intravenous injection; every other day; for three weeks) inhibits lung metastasis promoted by CAFs EVs in mice[2]. | Animal Model: | C57BL/6 J mice[2] | | Dosage: | 10 μg; every other day for 3 weeks; once every 2 weeks for 3 weeks | | Administration: | Intravenous injection (i.v.) | | Result: | Inhibited the formation of pre-metastatic microenvironment induced by EVs, inhibited SACC lung metastasis induced by EVs, and significantly increased integrin β1 of EVs. |
| | IC 50 | α2β1: 0.4 (α2β1 μM (IC50); α2β1: 26.8 (α2β1 μM (IC50); α1β1: 23.6 (α1β1 μM (IC50); α1β1: 24.4 (α1β1 μM (IC50); α11β1: 177 (α11β1 μM (IC50); α11β1: 3177 (α11β μM (IC50) | | storage | Store at -20°C |
| | TC-I 15 Preparation Products And Raw materials |
|