|
Product Name: | CNDAC | Synonyms: | 4-Amino-1-(2-cyano-2-deoxy-beta-D-arabinofuranosyl)-2(1H)-pyrimidinone;DFP-10917;2(1H)-Pyrimidinone, 4-amino-1-(2-cyano-2-deoxy-β-D-arabinofuranosyl)-;2'-Cyano-2'-deoxy-1-(b-D-arabinofuranosyl)cytosine;4-amino-1-(2-cyano-2-deoxy-β-D-arabinofuranosyl)-2(1H)-pyrimidinone | CAS: | 135598-68-4 | MF: | C10H12N4O4 | MW: | 252.23 | EINECS: | | Product Categories: | | Mol File: | 135598-68-4.mol | ![CNDAC Structure](CAS/20180808/GIF/135598-68-4.gif) |
| CNDAC Chemical Properties |
Boiling point | 596.9±60.0 °C(Predicted) | density | 1.75±0.1 g/cm3(Predicted) | storage temp. | Store at -20°C | solubility | Soluble in DMSO | pka | 12.78±0.70(Predicted) |
| CNDAC Usage And Synthesis |
Definition | ChEBI: CNDAC is a pyrimidine 2'-deoxyribonucleoside that is 2'-deoxycytidine having a cyano group in the 2'-position. It is the active metabolite of the anti-cancer drug, sapacitabine which is currently in clinical development for the treatment of hematologic malignancies and solid tumors. It has a role as an antineoplastic agent, a drug metabolite and a DNA synthesis inhibitor. It is a pyrimidine 2'-deoxyribonucleoside and a nitrile. |
| CNDAC Preparation Products And Raw materials |
|