| Company Name: |
Suzhou ARTK Medchem Co., Ltd. |
| Tel: |
+86-512-68323658 +86-18168183658 |
| Email: |
sales1@artkmedchem.com |
| Products Intro: |
Product Name:(1S,6S,7S,8R,8aR)-1,7,8-trihydroxy-1,2,3,5,6,7,8,8a-octahydroindolizin-6-yl]butanoate;hydrochloride
CAS:141117-12-6
Purity:0.98 Package:100KG;25KG;10KG;1KG
|
|
|
|
|
| Company Name: |
BOC Sciences
|
| Tel: |
1-631-485-4226; 16314854226 |
| Email: |
info@bocsci.com |
| Products Intro: |
Product Name:Celgosivir hydrochloride
CAS:141117-12-6
Purity:>=98% (HPLC) Remarks:Reach out to us for more information about custom solutions.
|
Celgosivir (hydrochloride) manufacturers
|
| | Celgosivir (hydrochloride) Basic information |
| Product Name: | Celgosivir (hydrochloride) | | Synonyms: | Celgosivir (hydrochloride);MBI 3253 hydrochloride;MDL 28574 hydrochloride;MX3253 hydrochloride;(1S,6S,7S,8R,8aR)-1,7,8-trihydroxy-1,2,3,5,6,7,8,8a-octahydroindolizin-6-yl] butanoate | | CAS: | 141117-12-6 | | MF: | C12H22ClNO5 | | MW: | 295.76 | | EINECS: | | | Product Categories: | | | Mol File: | 141117-12-6.mol |  |
| | Celgosivir (hydrochloride) Chemical Properties |
| storage temp. | Store at -20°C | | form | Solid | | color | White to gray | | Water Solubility | Water : ≥ 200 mg/mL (676.22 mM) |
| | Celgosivir (hydrochloride) Usage And Synthesis |
| Uses | Antiviral; inhibitor ( α-glucosidase). | | in vivo | Celgosivir fully protects AG129 mice from lethal infection with a mouse adapted dengue virus at a dose of 50 mg/kg twice daily (BID) for 5 days and is effective even after 48 h delayed treatment. The protection by celgosivir is dose- and schedule-dependent and that a twice-a-day regimen of 50, 25 or 10 mg/kg is more protective than a single daily dose of 100 mg/kg. Pharmacokinetics studies of celgosivir in mice shows that it rapidly metabolizes to castanospermine[4]. During primary infection with a mouse-adapted DENV strain S221, mice shows increased viremia on day 3, yet 80% survived day 10 with virus completely cleared by day 8[3]. | | IC 50 | HIV-1 |
| | Celgosivir (hydrochloride) Preparation Products And Raw materials |
|