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| | (R)-5-(2-(2,5-difluorophenyl)pyrrolidin-1-yl)-3-nitropyrazolo[1,5-a]pyrimidine Basic information |
| Product Name: | (R)-5-(2-(2,5-difluorophenyl)pyrrolidin-1-yl)-3-nitropyrazolo[1,5-a]pyrimidine | | Synonyms: | (R)-5-(2-(2,5-difluorophenyl)pyrrolidin-1-yl)-3-nitropyrazolo[1,5-a]pyrimidine;(2R)-2-(2,5-difluorophenyl)-1-{3-nitropyrazolo[1,5-a]pyrimidin-5-yl}pyrrolidine;5-[(2R)-2-(2,5-Difluorophenyl)-1-pyrrolidinyl]-3-nitr opyrazolo[1,5-a]pyrimidine;Larotrectinib Impurity 3（Larotrectinib DFP-PNPP Impurity）;(R)-5-(2-(2,5-Difluorophenyl)-1-pyrrolidinyl)-3-nitropyrazolo[1,5-a]pyrimidine;Pyrazolo[1,5-a]pyrimidine, 5-[(2R)-2-(2,5-difluorophenyl)-1-pyrrolidinyl]-3-nitro-;Larotrectinib DFP-PNPP Impurity;[(2R)-2-(2,5-Difluorophenyl)-1-pyrrolidinyl]-3-nitropyrazolo[1,5-a]pyrimidine | | CAS: | 1223404-90-7 | | MF: | C16H13F2N5O2 | | MW: | 345.3 | | EINECS: | | | Product Categories: | | | Mol File: | 1223404-90-7.mol | ![(R)-5-(2-(2,5-difluorophenyl)pyrrolidin-1-yl)-3-nitropyrazolo[1,5-a]pyrimidine Structure](CAS/20180601/GIF/1223404-90-7.gif) |
| | (R)-5-(2-(2,5-difluorophenyl)pyrrolidin-1-yl)-3-nitropyrazolo[1,5-a]pyrimidine Chemical Properties |
| density | 1.58±0.1 g/cm3(Predicted) | | pka | -0.73±0.40(Predicted) |
| | (R)-5-(2-(2,5-difluorophenyl)pyrrolidin-1-yl)-3-nitropyrazolo[1,5-a]pyrimidine Usage And Synthesis |
| | (R)-5-(2-(2,5-difluorophenyl)pyrrolidin-1-yl)-3-nitropyrazolo[1,5-a]pyrimidine Preparation Products And Raw materials |
| Raw materials | 4H-Pyrazolo[1,5-a]pyrimidin-5-one-->(2R)-2-(2,5-difluorophenyl)-1-{pyrazolo[1,5-a]pyrimidin-5-yl}pyrrolidine-->5-(2,5-difluorophenyl)-3,4-dihydro-2H-pyrrole-->3-nitropyrazolo[1,5-a]pyrimidin-5(4H)-one-->2,5-Difluorobenzaldehyde-->(R)-2-(2,5-DIFLUOROPHENYL)PYRROLIDINE HYDROCHLORIDE-->(2R)-2-(2,5-DIFLUOROPHENYL)PYRROLIDINE-->5-Hydroxypyrazolo[1,5-a]pyrimidine-->1-Bromo-2,5-difluorobenzene | | Preparation Products | LOXO-101 (sulfate) |
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