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Sulfadimethoxine

Sulfadimethoxine Suppliers list
Company Name: Wuhan Fortuna Chemical Co., Ltd
Tel: 86-27-59207850
Email: info@fortunachem.com
Products Intro: Product Name:Sulfadimethoxine base
CAS:122-11-2
Purity:98%-102; USP40 Package:25Kg/Drum;82USD
Company Name: Henan DaKen Chemical CO.,LTD.
Tel: +86-371-55531817
Email: info@dakenchem.com
Products Intro: Product Name:Sulfadimethoxine
CAS:122-11-2
Purity:99% Package:100g,500g,1kg,5kg,10kg
Company Name: Henan Tianfu Chemical Co.,Ltd.
Tel: 0371-55170693
Email: info@tianfuchem.com
Products Intro: CAS:122-11-2
Purity:99% Package:500G;1KG;5KG;25KG
Company Name: Hebei Chisure Biotechnology Co.LTD
Tel: +86 13292890173
Email: luna@speedgainpharma.com
Products Intro: Product Name:Sulfadimethoxine
CAS:122-11-2
Purity:99% Package:1ASSAYS;10USD
Company Name: career henan chemical co
Tel: +86-371-86658258
Email: sales@coreychem.com
Products Intro: Product Name:Sulfadimethoxine
CAS:122-11-2
Purity:98% Package:1KG;1USD

Lastest Price from Sulfadimethoxine manufacturers

  • Sulfadimethoxine base
  • US $82.00 / Kg/Drum
  • 2021-07-22
  • CAS:122-11-2
  • Min. Order: 100KG
  • Purity: 98%-102; USP40
  • Supply Ability: 5 tons
  • Sulfadimethoxine
  • US $15.00-10.00 / KG
  • 2021-07-13
  • CAS:122-11-2
  • Min. Order: 1KG
  • Purity: 99%+ HPLC
  • Supply Ability: Monthly supply of 1 ton
Sulfadimethoxine Basic information
Brand Name(s) in US
Product Name:Sulfadimethoxine
Synonyms:deposul;diasulfa;madroxin;madroxine;maxulvet;memcozine;metoxidon;n(sup1)-(2,6-dimethoxy-4-pyrimidinyl)-sulfanilamid
CAS:122-11-2
MF:C12H14N4O4S
MW:310.33
EINECS:204-523-7
Product Categories:MADRIBON;APIs;Antibiotics for Research and Experimental Use;Biochemistry;Sulfonamides (Antibiotics for Research and Experimental Use);Amines;Aromatics;Intermediates & Fine Chemicals;Pharmaceuticals;Sulfur & Selenium Compounds
Mol File:122-11-2.mol
Sulfadimethoxine Structure
Sulfadimethoxine Chemical Properties
Melting point 200 °C
Boiling point 265.5°C (rough estimate)
density 1.4006 (rough estimate)
refractive index 1.6270 (estimate)
storage temp. 2-8°C
solubility NH4OH 1 M: 50 mg/mL, clear, faintly yellow
pkapKa 5.94(H2O t = 25.0±0.5 I = 0.2) (Uncertain)
form neat
Water Solubility 46.3mg/L(37 ºC)
Merck 14,8905
BRN 306856
CAS DataBase Reference122-11-2(CAS DataBase Reference)
EPA Substance Registry SystemSulfadimethoxine (122-11-2)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38-43
Safety Statements 26-36/37-24/25-23
RIDADR 3249
WGK Germany 3
RTECS WO9030000
8
HazardClass 6.1(b)
PackingGroup III
HS Code 29350090
ToxicityLD50 orally in mice: >10 g/kg (Seki)
MSDS Information
ProviderLanguage
Sulfadimethoxine English
SigmaAldrich English
Sulfadimethoxine Usage And Synthesis
Brand Name(s) in USAlbon, Bactrovet, and generic
Chemical PropertiesWhite Solid
OriginatorMadribon,Roche,US,1958
UsesAntibacterial.
DefinitionChEBI: A sulfonamide consisting of pyrimidine having methoxy substituents at the 2- and 6-positions and a 4-aminobenzenesulfonamido group at the 4-position.
Manufacturing Process1.4 g of 4-phenylsulfonyl-2,6-dimethoxypyrimidine and 4 g of sodium sulfanilamide (both dried over potassium hydroxide) were very finely ground and heated in an oil bath for 10 hours at 120°C (inside temperature). The reaction mixture was taken up in 30 ml of water and treated with 3 ml of 2 N sodium hydroxide solution. After standing for one hour at 0°C, the turbid solution was filtered and the filtrate was made alkaline with sodium carbonate. After again standing for one hour at 0°C, the precipitate was filtered off (1.9 g of regenerated sulfanilamide) and the filtrate was neutralized with acetic acid, whereupon crystallization resulted. The isolated crystals of 4-sulfanilamido- 2,6-dimethoxypyrimidine weighed 1.3 g (84% of theory), melting point 190°C to 196°C.
Therapeutic FunctionAntibacterial
Pharmaceutical Applications2,4-Dimethoxy-6-sulfanilamido-1,3-diazine. A rapidly absorbed compound with a long half-life (38–40 h) and a high degree of protein binding (98%). Renal clearance is very slow, and daily dosage maintains adequate plasma levels.
Safety ProfileModerately toxic by intraperitoneal, intravenous, and subcutaneous routes. An experimental teratogen. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of SOx and NOx.
Veterinary Drugs and TreatmentsSulfadimethoxine injection and tablets are approved for use in dogs and cats for respiratory, genitourinary, enteric and soft tissue infections caused by susceptible organisms. Sulfadimethoxine is used in the treatment of coccidiosis in dogs although not approved for this indication.
In horses, sulfadimethoxine injection is approved for the treatment of respiratory infections caused by Streptococcus equi.
In cattle, the drug is approved for treating shipping fever complex, calf diphtheria, bacterial pneumonia and foot rot caused by susceptible organisms.
In poultry, sulfadimethoxine is added to drinking water to treat coccidiosis, fowl cholera, and infectious coryza.
Sulfadimethoxine Preparation Products And Raw materials
Raw materials2-Amino-4,6-dimethoxypyrimidine
Tag:Sulfadimethoxine(122-11-2) Related Product Information
4-(Acetylamino)-N-(2,6-dimethoxy-4-pyrimidinyl)benzenesulfonamide Sulfadimethoxine-d6 SULFADIMETHOXINE-D4 Sulfanilic acid p-[[(4-chlorobutyl)sulphonyl]amino]benzenesulphonamide N-acetylsulphanilic acid 4-Amino-2,6-dimethoxypyrimidine 1,3-di(4-sulfamoylphenyl)triazene N-(2,6-DIMETHOXY-4-PYRIMIDINYL)-4-[(3-OXO-3-PHENYLPROPYL)AMINO]BENZENESULFONAMIDE SALAZODIMETHOXINE N-(2,6-DIMETHOXY-4-PYRIMIDINYL)-4-{[3-(4-METHOXYPHENYL)-3-OXOPROPYL]AMINO}BENZENESULFONAMIDE 3-[4-(2,6-DIMETHOXY-PYRIMIDIN-4-YLSULFAMOYL)-PHENYLCARBAMOYL]-ACRYLIC ACID N-[4-(2,6-DIMETHOXY-PYRIMIDIN-4-YLSULFAMOYL)-PHENYL]-PHTHALAMIC ACID SULFADIMETHOXINE SODIUM SALT,Sodium sulfadimethoxine N-[4-(2,6-DIMETHOXY-PYRIMIDIN-4-YLSULFAMOYL)-PHENYL]-SUCCINAMIC ACID Sulfachoropyrazine sodium Sulfachloropyridazine sodium SULFACHLOROPYRIDAZINE