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BOC Sciences
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1-631-485-4226; 16314854226 |
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| Products Intro: |
Product Name:Banoxantrone dihydrochloride
CAS:252979-56-9
Remarks:Banoxantrone dihydrochloride, a bioreductive prodrug, can be reduced to a stable, DNA-affinic compound AQ4, which is a potent topoisomerase II inhibitor, and exhibits little to no cytotoxic activity a
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| | Banoxantrone (dihydrochloride) Basic information |
| Product Name: | Banoxantrone (dihydrochloride) | | Synonyms: | Banoxantrone 2HCl;1,4-Bis[[2-(dimethyloxidoamino)ethyl]amino]-5,8-dihydroxy-9,10-anthracenedione dihydrochloride;AQ4N dihydrochloride;Banoxantrone dihydrochloride >=98% (HPLC) | | CAS: | 252979-56-9 | | MF: | C22H29ClN4O6 | | MW: | 480.95 | | EINECS: | | | Product Categories: | | | Mol File: | 252979-56-9.mol |  |
| | Banoxantrone (dihydrochloride) Chemical Properties |
| storage temp. | Store at -20°C, protect from light, stored under nitrogen | | solubility | Soluble to 50 mM in water and to 25 mM in DMSO | | Water Solubility | Water : 25 mg/mL (48.32 mM) |
| | Banoxantrone (dihydrochloride) Usage And Synthesis |
| Uses | Banoxantrone (AQ4N) is a hypoxia-activated prodrug of topoisomerase II inhibitor AQ4 (Bioreductive AQ4 precursor). studies have shown that its has also exhibited anti-tumor efficacy in vivo when combined with oxic cell cytotoxins. | | storage | Store at +4°C |
| | Banoxantrone (dihydrochloride) Preparation Products And Raw materials |
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