Azide-PEG3-Desthiobiotin manufacturers
|
| Azide-PEG3-Desthiobiotin Basic information |
Product Name: | Azide-PEG3-Desthiobiotin | Synonyms: | CAS_1426828-06-9;Desthiobiotin-PEG4-Azide;Azide-PEG3-Desthiobiotin;N-[2-[2-[2-(2-Azidoethoxy)ethoxy]ethoxy]ethyl]-6-[(4R,5S)-5-methyl-2-oxoimidazolidin-4-yl]hexanamide | CAS: | 1426828-06-9 | MF: | C18H34N6O5 | MW: | 414.51 | EINECS: | | Product Categories: | | Mol File: | 1426828-06-9.mol | |
| Azide-PEG3-Desthiobiotin Chemical Properties |
form | clear liquid | color | Colorless to Yellow to Orange |
| Azide-PEG3-Desthiobiotin Usage And Synthesis |
Description | Desthiobiotin is a single-ring, sulfur-free analog of biotin that binds to streptavidin with nearly equal specificity but less affinity than biotin (Kd?= 1011?vs. 1015M, respectively). Consequently, desthiobiotinylated proteins can be eluted readily and specifically from streptavidin affinity resin using mild conditions based on competitive displacement with free biotin. For pull-down experiments with biological samples, this soft-release characteristic of desthiobiotin also helps to minimize co-purification of endogenous biotinylated molecules, which remain bound to streptavidin upon elution of the target protein complexes with free biotin. |
| Azide-PEG3-Desthiobiotin Preparation Products And Raw materials |
|