|
|
| | PHENYLMERCURIC NITRATE Basic information |
| Product Name: | PHENYLMERCURIC NITRATE | | Synonyms: | Mercuriphenyl nitrate;PHENYLMERCURIC NITRATE;PHENYLMERCURIC NITRATE, BASIC;PHENYLMERCURY NITRATE;PHENYLMERCURY NITRATE BASIC;cmpd.withhydroxyphenylmercury(1:1);dz;Gyne-merfen | | CAS: | 8003-05-2 | | MF: | C12H11Hg2NO4 | | MW: | 634.4 | | EINECS: | 620-403-0 | | Product Categories: | | | Mol File: | 8003-05-2.mol |  |
| | PHENYLMERCURIC NITRATE Chemical Properties |
| Melting point | 175-185 °C (dec.) (lit.) | | vapor pressure | 0.0000019 hPa at 20°C | | storage temp. | Store below +30°C. | | form | Solid | | color | White crystalline | | PH Range | 6.6 | | Water Solubility | soluble ~1250 parts H2O; slightly soluble alcohol [MER06] | | Merck | 14,7302 | | CAS DataBase Reference | 8003-05-2(CAS DataBase Reference) |
| Hazard Codes | T,N | | Risk Statements | 25-34-48/24/25-50/53 | | Safety Statements | 23-24/25-37-45-60-61 | | RIDADR | UN 1895 6.1/PG 2 | | WGK Germany | 3 | | RTECS | OW8575000 | | HazardClass | 6.1 | | PackingGroup | II | | HS Code | 28521000 | | Toxicity | LD50 in mice (mg/g): 0.045 s.c.; 0.027 i.v. (Wien) |
| | PHENYLMERCURIC NITRATE Usage And Synthesis |
| Chemical Properties | white powder | | Uses | Pharmaceutic aid (antimicrobial). Tree wound dressing. | | General Description | Phenylmercury nitrate is a mercury-based organic compound known to have antibacterial and antifungal activities. It is also used as a preservative for parenteral injections. | | Clinical Use | Phenylmercuric nitrate is a mixture of phenylmercuric nitrateand phenylmercuric hydroxide. It occurs as a whitecrystalline material that is sparingly soluble in water andslightly soluble in alcohol. It is used in concentrations of1:10,000 to 1:50,000 to preserve injectable drugs againstbacterial contamination. A disadvantage to organomercurialsis that their bacteriostatic efficacy is reduced in the presenceof serum. | | Purification Methods | When recrystallised from water or aqueous EtOH, it has m 191-191.5o, and from 95% EtOH it has m 186.5o [Challanger & Rothstein J Chem Soc I 1258 1934]. When recrystallised from *C6H6 or CHCl3, it has m 131-131.5o [Morton et al. J Am Chem Soc 69 908 1947.] [Beilstein 16 III 1348, 16 IV 1721.] |
| | PHENYLMERCURIC NITRATE Preparation Products And Raw materials |
|