| Company Name: |
Atlas antibodies |
| Tel: |
46-854595850 |
| Email: |
order@atlasantibodies.com |
| Company Name: |
Merck KGaA |
| Tel: |
21-20338288 |
| Email: |
ordercn@merckgroup.com |
|
| | ANTI-RIBONUCLEASE L Basic information |
| Product Name: | ANTI-RIBONUCLEASE L | | Synonyms: | Monoclonal Anti-RNase L antibody produced in mouse;Anti-RNASEL antibody produced in rabbit;ANTI-RIBONUCLEASE L;MONOCLONAL ANTI-RNASE L;Anti-2-5A-dependent ribonuclease;Anti-Ribonuclease 4;Anti-2-5A-dependent RNase;Anti-RNase L | | CAS: | | | MF: | | | MW: | 0 | | EINECS: | | | Product Categories: | | | Mol File: | Mol File | ![ANTI-RIBONUCLEASE L Structure]() |
| | ANTI-RIBONUCLEASE L Chemical Properties |
| storage temp. | −20°C | | form | buffered aqueous solution | | biological source | rabbit |
| WGK Germany | 3 | | Storage Class | 10 - Combustible liquids |
| | ANTI-RIBONUCLEASE L Usage And Synthesis |
| Uses | Anti-RNASEL antibody produced in rabbit is suitable for western blotting at a concentration of 1 μg/ml. | | Biological Activity | RNASEL (ribonuclease L), an endonuclease, is involved in the molecular mechanism of interferon (IFN) and RNA degradation pathway. It is activated by interferon-regulated 2-5A system. It inhibits the protein synthesis by cleaving mRNA on the 3μ end. This regulatory protein is controlled by RNase L inhibitor (RLI) which inhibits 2-5A binding to RNase L, thereby switching off the 2-5A/RNase L system. It may have an antiproliferative effect on IFNα. It helps to induce the down-regulation of mitochondrial mRNAs which degrades cellular ATP levels and suppresses mitochondrial function. Mutation in the RNASEL is linked to the hereditary prostate cancer 1 (HPC1). |
| | ANTI-RIBONUCLEASE L Preparation Products And Raw materials |
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