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| | Ethyl 3-amino-4-pyrazolecarboxylate Basic information |
| | Ethyl 3-amino-4-pyrazolecarboxylate Chemical Properties |
| Melting point | 105-107 °C(lit.) | | Boiling point | 278.95°C (rough estimate) | | density | 1.3092 (rough estimate) | | refractive index | 1.6500 (estimate) | | storage temp. | 2-8°C | | solubility | Chloroform (Sparingly), Methanol (Slightly) | | pka | 12.98±0.50(Predicted) | | form | Crystalline Powder | | color | White to yellow | | BRN | 4964 | | Stability: | Light sensitive | | CAS DataBase Reference | 6994-25-8(CAS DataBase Reference) | | NIST Chemistry Reference | 3-Amino-4-carbethoxypyrazole(6994-25-8) |
| | Ethyl 3-amino-4-pyrazolecarboxylate Usage And Synthesis |
| Chemical Properties | Off-White Powder | | Uses | Ethyl 3-Amino-4-pyrazolecarboxylate (Allopurinol EP Impurity D) is an impurity of Allopurinol (A547300), a pyrazole derivative that has been shown to induce neoplasm immunogenicity. | | General Description | Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards |
| | Ethyl 3-amino-4-pyrazolecarboxylate Preparation Products And Raw materials |
| Raw materials | Acetic acid-->Hydrazinium hydroxide solution-->Triethyl orthoformate-->Ethyl cyanoacetate-->HYDRAZINE-->Ethyl (ethoxymethylene)cyanoacetate | | Preparation Products | Allopurinol-->Pyrazolo[1,5-a]pyrimidine-3-carboxylic acid, 5,7-dichloro-, ethyl ester-->1-H-pyrazole-4-carboxylic acid,3-broMo,ethyl ester-->5-AMINO-4-CARBETHOXY-1-PHENYLPYRAZOLE-->ethyl 5-(4-bromophenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxylate-->1H-Pyrazole-4-carboxylic acid, 3-iodo-1-(tetrahydro-2H-pyran-2-yl)-, ethyl ester-->ETHYL 5-(4-FLUOROPHENYL)-7-(TRIFLUOROMETHYL)PYRAZOLO[1,5-A]PYRIMIDINE-3-CARBOXYLATE |
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