- N-BOC-4-Hydroxypiperidine
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- $200.00 / 1KG
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2024-01-02
- CAS:109384-19-2
- Min. Order: 1KG
- Purity: 99%, 99.5% Sublimated
- Supply Ability: g-kg-tons, free sample is available
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| | N-BOC-4-Hydroxypiperidine Basic information |
| | N-BOC-4-Hydroxypiperidine Chemical Properties |
| Melting point | 61-65 °C (lit.) | | Boiling point | 292.3±33.0 °C(Predicted) | | density | 1.107±0.06 g/cm3(Predicted) | | storage temp. | Keep in dark place,Sealed in dry,Room Temperature | | solubility | Chloroform, Ethyl Acetate | | form | Powder | | pka | 14.80±0.20(Predicted) | | color | White to cream | | BRN | 7202094 | | InChI | InChI=1S/C10H19NO3/c1-10(2,3)14-9(13)11-6-4-8(12)5-7-11/h8,12H,4-7H2,1-3H3 | | InChIKey | PWQLFIKTGRINFF-UHFFFAOYSA-N | | SMILES | N1(C(OC(C)(C)C)=O)CCC(O)CC1 | | CAS DataBase Reference | 109384-19-2(CAS DataBase Reference) |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 26-36-37/39 | | WGK Germany | 3 | | HazardClass | IRRITANT | | HS Code | 29339900 |
| | N-BOC-4-Hydroxypiperidine Usage And Synthesis |
| Chemical Properties | White to cream powder | | Uses | Used in a synthesis of N-heterocyclic alkyl ethers via the Mitsunobu reaction. | | Uses | N-Boc-4-hydroxypiperidine is a 4-hydroxypyridine with a boc protecting group used in the preparation of neurologically active agents and other pharmaceutical compounds. | | Preparation | A mixture of 4-hydroxypiperidine (10.0 g, 98. 9 mmol), aqueous sodiumhydrogen carbonate (150 mL, 1 M), DI-FERT-BUTYL dicarbonate (21. 6 g, 98.9 mmol) and dichloromethane was stirred for 15 h. The phases were separated and the product (N-BOC-4-Hydroxypiperidine) was isolated as an oil in quantitative yield (19.9 g).
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| | N-BOC-4-Hydroxypiperidine Preparation Products And Raw materials |
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