|
|
| | ACETYLSALICYLSALICYLIC ACID Basic information |
| | ACETYLSALICYLSALICYLIC ACID Chemical Properties |
| Melting point | 153-160 °C | | Boiling point | 361.5°C (rough estimate) | | density | 1.346 | | refractive index | 1.4600 (estimate) | | storage temp. | Sealed in dry,Room Temperature | | solubility | Chloroform (Sparingly), DMSO (Sparingly), Methanol (Slightly) | | pka | 2.94±0.36(Predicted) | | color | White to Off-White | | Water Solubility | 20mg/L(21 ºC) | | EPA Substance Registry System | 2-Carboxyphenyl 2-(acetyloxy)benzoate (530-75-6) |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 24/25 | | HS Code | 29182900 |
| Provider | Language |
|
ACROS
| English |
| | ACETYLSALICYLSALICYLIC ACID Usage And Synthesis |
| Chemical Properties | white to almost white fine crystalline powder | | Uses | Acetylsalicylic Acid Impurity C | | Uses | analgesic, antipyretic | | Uses | Antiinflammatory;Cyclooxygenase inhibitor | | Definition | ChEBI: 2-[(2-acetyloxyphenyl)-oxomethoxy]benzoic acid is a carbonyl compound. | | Purification Methods | Crystallise the analgesic from dilute AcOH or EtOH (m 161-162o), MeOH (m 165-168o), and *C6H6/EtOH (m 163-165o). Its solubilities in boiling Et2O, *C6H6 and EtOH are 1.4%, 2.2% and 33%, respectively. [Baker et al. J Chem Soc 201 1951, Garrett et al. J Am Pharm Soc 48 684 1959, Beilstein 10 I 41, 10 II 54, 10 IV 165.] |
| | ACETYLSALICYLSALICYLIC ACID Preparation Products And Raw materials |
|